In vivo single‐cell transcriptomics reveal Klebsiella pneumoniae skews lung macrophages to promote infection
Author:
Affiliation:
1. Wellcome‐Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences Queen's University Belfast Belfast UK
Funder
Biotechnology and Biological Sciences Research Council
Medical Research Council
Publisher
EMBO
Subject
Molecular Medicine
Link
https://onlinelibrary.wiley.com/doi/pdf/10.15252/emmm.202216888
Reference76 articles.
1. Influenza-induced monocyte-derived alveolar macrophages confer prolonged antibacterial protection
2. Acquired resistance to innate immune clearance promotes Klebsiella pneumoniae ST258 pulmonary infection
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4. Recruitment and training of alveolar macrophages after pneumococcal pneumonia
5. Reference-based analysis of lung single-cell sequencing reveals a transitional profibrotic macrophage
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