Haematopoietic stem cell gene therapy with IL ‐1Ra rescues cognitive loss in mucopolysaccharidosis IIIA-Reference-Cited by-同舟云学术

Haematopoietic stem cell gene therapy with IL ‐1Ra rescues cognitive loss in mucopolysaccharidosis IIIA

Published:2020-02-14 Issue:3 Volume:12 Page:
ISSN:1757-4676
Container-title:EMBO Molecular Medicine
language:en
Short-container-title:EMBO Mol Med

Author:

Parker Helen¹,Ellison Stuart M¹,Holley Rebecca J¹,O'Leary Claire¹,Liao Aiyin¹,Asadi Jalal¹,Glover Emily¹,Ghosh Arunabha²,Jones Simon²,Wilkinson Fiona L³⁴,Brough David⁵^ORCID,Pinteaux Emmanuel⁵,Boutin Hervé⁵⁶,Bigger Brian W¹^ORCID

Affiliation:

1. Stem Cell and Neurotherapies Division of Cell Matrix Biology & Regenerative Medicine Faculty of Biology, Medicine and Health Manchester Academic Health Science Centre University of Manchester Manchester UK

2. Royal Manchester Children's Hospital Manchester University Hospitals NHS Foundation Trust Manchester UK

3. Division of Biomedical Sciences School of Healthcare Science Manchester Metropolitan University Manchester UK

4. The Centre for Bioscience Manchester Metropolitan University Manchester UK

5. Division of Neuroscience & Experimental Psychology Faculty of Biology, Medicine and Health Manchester Academic Health Science Centre University of Manchester Manchester UK

6. Wolfson Molecular Imaging Centre University of Manchester Manchester UK

Publisher

EMBO

Subject

Molecular Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.15252/emmm.201911185

Reference90 articles.

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4. Early Neurodegeneration Progresses Independently of Microglial Activation by Heparan Sulfate in the Brain of Mucopolysaccharidosis IIIB Mice

5. Interleukin-1: A master regulator of neuroinflammation

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