Pharmacological reversal of synaptic and network pathology in human MECP2 ‐KO neurons and cortical organoids-Reference-Cited by-同舟云学术

Pharmacological reversal of synaptic and network pathology in human MECP2 ‐KO neurons and cortical organoids

Published:2020-12-08 Issue:1 Volume:13 Page:
ISSN:1757-4676
Container-title:EMBO Molecular Medicine
language:en
Short-container-title:EMBO Mol Med

Author:

Trujillo Cleber A¹^ORCID,Adams Jason W¹²³,Negraes Priscilla D¹⁴,Carromeu Cassiano¹⁴,Tejwani Leon¹,Acab Allan¹,Tsuda Ben²⁵,Thomas Charles A¹,Sodhi Neha⁴,Fichter Katherine M⁴,Romero Sarah⁴,Zanella Fabian⁴,Sejnowski Terrence J⁵⁶⁷,Ulrich Henning⁸,Muotri Alysson R¹³^ORCID

Affiliation:

1. Department of Pediatrics/Rady Children's Hospital Department of Cellular & Molecular Medicine School of Medicine University of California San Diego La JollaCA USA

2. Department of Neurosciences School of Medicine University of California San Diego La JollaCA USA

3. Center for Academic Research and Training in Anthropogeny University of California San Diego La JollaCA USA

4. StemoniX Inc Maple Grove MN USA

5. Computational Neurobiology Laboratory Salk Institute for Biological Studies La JollaCA USA

6. Institute for Neural Computation University of California San Diego La JollaCA USA

7. Division of Biological Sciences University of California San Diego La JollaCA USA

8. Departamento de Bioquímica Instituto de Química Universidade de São Paulo São Paulo Brazil

Funder

National Institute of Mental Health

National Institutes of Health

National Institute of General Medical Sciences

National Institute on Alcohol Abuse and Alcoholism

Publisher

EMBO

Subject

Molecular Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.15252/emmm.202012523

Reference62 articles.

1. Brain Organoids as Tools for Modeling Human Neurodevelopmental Disorders

2. Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2

3. Towards a better diagnosis and treatment of Rett syndrome: a model synaptic disorder

4. Impact on GABA systems in monogenetic developmental CNS disorders: Clues to symptomatic treatment

5. The GABAA Receptor as a Therapeutic Target for Neurodevelopmental Disorders

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