A high‐affinity, bivalent PDZ domain inhibitor complexes PICK 1 to alleviate neuropathic pain-Reference-Cited by-同舟云学术

A high‐affinity, bivalent PDZ domain inhibitor complexes PICK 1 to alleviate neuropathic pain

Published:2020-04-30 Issue:6 Volume:12 Page:
ISSN:1757-4676
Container-title:EMBO Molecular Medicine
language:en
Short-container-title:EMBO Mol Med

Author:

Christensen Nikolaj R¹²,De Luca Marta¹,Lever Michael B¹,Richner Mette³,Hansen Astrid B¹,Noes‐Holt Gith¹,Jensen Kathrine L¹,Rathje Mette¹,Jensen Dennis Bo⁴,Erlendsson Simon⁵,Bartling Christian RO²,Ammendrup‐Johnsen Ina¹,Pedersen Sofie E¹,Schönauer Michèle²,Nissen Klaus B²,Midtgaard Søren R⁶^ORCID,Teilum Kaare⁵,Arleth Lise⁶,Sørensen Andreas T¹,Bach Anders²,Strømgaard Kristian²,Meehan Claire F⁴,Vægter Christian B³,Gether Ulrik¹,Madsen Kenneth L¹^ORCID

Affiliation:

1. Molecular Neuropharmacology and Genetics Laboratory Department of Neuroscience Faculty of Health and Medical Sciences University of Copenhagen Copenhagen Denmark

2. Center for Biopharmaceuticals Department of Drug Design and Pharmacology Faculty of Health and Medicine University of Copenhagen Copenhagen Denmark

3. Danish Research Institute of Translational Neuroscience (DANDRITE) Nordic‐EMBL Partnership for Molecular Medicine Department of Biomedicine Aarhus University Aarhus C Denmark

4. Department of Neuroscience Faculty of Health and Medical Sciences University of Copenhagen Copenhagen Denmark

5. Structural biology and NMR Laboratory Department of Biology University of Copenhagen Copenhagen Denmark

6. Structural Biophysics Niels Bohr Institute University of Copenhagen Copenhagen Denmark

Funder

Sundhed og Sygdom, Det Frie Forskningsråd

Teknologi og Produktion, Det Frie Forskningsråd

Lundbeckfonden

Novo Nordisk Fonden

Publisher

EMBO

Subject

Molecular Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.15252/emmm.201911248

Reference92 articles.

1. Treatment of Ischemic Brain Damage by Perturbing NMDA Receptor- PSD-95 Protein Interactions

2. Synapto-depressive effects of amyloid beta require PICK1

3. Spinal cord protein interacting with C kinase 1 is required for the maintenance of complete Freund's adjuvant-induced inflammatory pain but not for incision-induced post-operative pain

4. Design and Synthesis of Highly Potent and Plasma-Stable Dimeric Inhibitors of the PSD-95-NMDA Receptor Interaction

5. Structure–activity relationships of a small-molecule inhibitor of the PDZ domain of PICK1

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1. Unconventional PDZ Recognition Revealed in α7 nAChR-PICK1 Complexes;ACS Chemical Neuroscience;2024-05-01

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