Beclin‐1‐mediated activation of autophagy improves proximal and distal urea cycle disorders

Author:

Soria Leandro R1ORCID,Gurung Sonam2,De Sabbata Giulia3,Perocheau Dany P2ORCID,De Angelis Angela1,Bruno Gemma1,Polishchuk Elena1,Paris Debora4,Cuomo Paola4,Motta Andrea4,Orford Michael2,Khalil Youssef2ORCID,Eaton Simon2,Mills Philippa B2,Waddington Simon N25,Settembre Carmine1ORCID,Muro Andrés F3ORCID,Baruteau Julien26ORCID,Brunetti‐Pierri Nicola17ORCID

Affiliation:

1. Telethon Institute of Genetics and Medicine Pozzuoli Italy

2. UCL Great Ormond Street Institute of Child Health London UK

3. International Centre for Genetic Engineering and Biotechnology Trieste Italy

4. Institute of Biomolecular Chemistry, National Research Council Pozzuoli Italy

5. Wits/SAMRC Antiviral Gene Therapy Research Unit Faculty of Health Sciences University of the Witwatersrand Johannesburg South Africa

6. Metabolic Medicine Department Great Ormond Street Hospital for Children NHS Foundation Trust London UK

7. Department of Translational Medicine Federico II University Naples Italy

Funder

Fondazione Telethon

Ministero dell’Istruzione, dell’Università e della Ricerca

Medical Research Council

Publisher

EMBO

Subject

Molecular Medicine

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