Functional drug screening reveals anticonvulsants as enhancers of mTOR‐independent autophagic killing of Mycobacterium tuberculosis through inositol depletion-Reference-Cited by-同舟云学术

Functional drug screening reveals anticonvulsants as enhancers of mTOR‐independent autophagic killing of Mycobacterium tuberculosis through inositol depletion

Published:2014-12-22 Issue:2 Volume:7 Page:127-139
ISSN:1757-4676
Container-title:EMBO Molecular Medicine
language:en
Short-container-title:EMBO Mol Med

Author:

Schiebler Mark¹,Brown Karen¹²,Hegyi Krisztina¹,Newton Sandra M³,Renna Maurizio⁴,Hepburn Lucy¹,Klapholz Catherine¹,Coulter Sarah¹,Obregón‐Henao Andres⁵,Henao Tamayo Marcela⁵,Basaraba Randall⁵,Kampmann Beate³,Henry Katherine M⁶,Burgon Joseph⁶,Renshaw Stephen A⁶,Fleming Angeleen⁴,Kay Robert R⁷,Anderson Karen E⁸,Hawkins Phillip T⁸,Ordway Diane J⁵,Rubinsztein David C⁴,Floto Rodrigo Andres¹²

Affiliation:

1. Department of Medicine Cambridge Institute for Medical Research University of Cambridge Cambridge UK

2. Cambridge Centre for Lung Infection Papworth Hospital Cambridge UK

3. Department of Paediatric Infectious Diseases and Allergy Imperial College London London UK

4. Department of Medical Genetics Cambridge Institute for Medical Research University of Cambridge Cambridge UK

5. Department of Microbiology, Immunology and Pathology Colorado State University Fort Collins Colorado USA

6. Department of Infection and Immunity University of Sheffield Western Bank Sheffield UK

7. MRC Laboratory of Molecular Biology Cambridge UK

8. The Inositide Laboratory Babraham Institute Babraham Research Campus Cambridge UK

Publisher

EMBO

Subject

Molecular Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.15252/emmm.201404137

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