The immune suppressive microenvironment affects efficacy of radio‐immunotherapy in brain metastasis

Author:

Niesel Katja1,Schulz Michael12,Anthes Julian1,Alekseeva Tijna1,Macas Jadranka34,Salamero‐Boix Anna12,Möckl Aylin1,Oberwahrenbrock Timm56,Lolies Marco1,Stein Stefan1,Plate Karl H347,Reiss Yvonne347,Rödel Franz478,Sevenich Lisa147ORCID

Affiliation:

1. Institute for Tumor Biology and Experimental Therapy Georg‐Speyer‐Haus Frankfurt am Main Germany

2. Biological Sciences Faculty 15 Goethe University Frankfurt Frankfurt am Main Germany

3. Institute of Neurology (Edinger Institute) University HospitalGoethe University Frankfurt am Main Germany

4. Frankfurt Cancer Institute (FCI)Goethe University Frankfurt Frankfurt am Main Germany

5. Fraunhofer Institute for Translational Medicine and Pharmacology (ITMP) Frankfurt am Main Germany

6. Fraunhofer Cluster of Excellence Immune Mediated Diseases (CIMD) Frankfurt am Main Germany

7. German Cancer Consortium (DKTK)Partner Site Frankfurt/Mainz, Germany and German Cancer Research Center (DKFZ) Heidelberg Germany

8. Department of Radiotherapy and Oncology Goethe University Frankfurt Frankfurt am Main Germany

Funder

Deutsche Krebshilfe

Deutsche Forschungsgemeinschaft

Publisher

EMBO

Subject

Molecular Medicine

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