The HSP40 chaperone Ydj1 drives amyloid beta 42 toxicity

Author:

Ring Julia1ORCID,Tadic Jelena12ORCID,Ristic Selena1ORCID,Poglitsch Michael1,Bergmann Martina1ORCID,Radic Nemanja1,Mossmann Dirk3ORCID,Liang YongTian45ORCID,Maglione Marta45ORCID,Jerkovic Andrea1,Hajiraissi Roozbeh6,Hanke Marcel6ORCID,Küttner Victoria7,Wolinski Heimo12ORCID,Zimmermann Andreas12ORCID,Domuz Trifunović Lana1,Mikolasch Leonie1,Moretti Daiana N89,Broeskamp Filomena1,Westermayer Julia1,Abraham Claudia1ORCID,Schauer Simon1,Dammbrueck Christopher1,Hofer Sebastian J1ORCID,Abdellatif Mahmoud101112ORCID,Grundmeier Guido6ORCID,Kroemer Guido111213ORCID,Braun Ralf J1415ORCID,Hansen Niklas6ORCID,Sommer Cornelia1,Ninkovic Mirjana1,Seba Sandra1,Rockenfeller Patrick116ORCID,Vögtle Friederike‐Nora31718ORCID,Dengjel Jörn719ORCID,Meisinger Chris3ORCID,Keller Adrian6ORCID,Sigrist Stephan J45,Eisenberg Tobias12ORCID,Madeo Frank12ORCID

Affiliation:

1. Institute of Molecular Biosciences NAWI Graz University of Graz Graz Austria

2. Field of Excellence BioHealth University of Graz Graz Austria

3. Institute for Biochemistry and Molecular Biology ZBMZ, Medical Faculty and CIBSS ‐ Centre for Integrative Biological Signalling Studies University of Freiburg Freiburg Germany

4. NeuroCure Charité Berlin Berlin Germany

5. Institute for Biology Freie Universität Berlin Berlin Germany

6. Technical and Macromolecular Chemistry Paderborn University Paderborn Germany

7. Department of Dermatology Medical Center Freiburg Institute for Advanced Studies (FRIAS) University of Freiburg Freiburg Germany

8. Institute of Biochemistry and Molecular Biology ZBMZ Faculty of Medicine University of Freiburg Freiburg Germany

9. Faculty of Biology University of Freiburg Freiburg Germany

10. Department of Cardiology Medical University of Graz Graz Austria

11. Centre de Recherche des Cordeliers Equipe labellisée par la Ligue contre le cancer Université de Paris Sorbonne Université, Inserm U1138, Institut Universitaire de France Paris France

12. Metabolomics and Cell Biology Platforms Institut Gustave Roussy Villejuif France

13. Institut du Cancer Paris CARPEM Department of Biology Hôpital Européen Georges Pompidou, AP‐HP Paris France

14. Research Division for Neurodegenerative Diseases Center for Biosciences Department of Medicine Faculty of Medicine and Dentistry Danube Private University Krems Austria

15. Cell Biology University of Bayreuth Bayreuth Germany

16. Chair of Biochemistry and Molecular Medicine Center for Biomedical Education and Research (ZBAF) University of Witten/Herdecke (UW/H) Witten Germany

17. Center for Molecular Biology of Heidelberg University (ZMBH) DKFZ‐ZMBH Alliance Heidelberg Germany

18. Network Aging Research Heidelberg University Heidelberg Germany

19. Department of Biology University of Fribourg Fribourg Switzerland

Funder

Austrian Science Fund

Agence Nationale de la Recherche

Fondation pour la Recherche Médicale

Fondation ARC pour la Recherche sur le Cancer

Deutsche Forschungsgemeinschaft

Canton de Fribourg

Ligue Contre le Cancer

Institut National Du Cancer

Institut Universitaire de France

Labex Immuno-Oncology

Mark Foundation For Cancer Research

Seerave Foundation

Publisher

EMBO

Subject

Molecular Medicine

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