CDK7/12/13 inhibition targets an oscillating leukemia stem cell network and synergizes with venetoclax in acute myeloid leukemia-Reference-Cited by-同舟云学术

CDK7/12/13 inhibition targets an oscillating leukemia stem cell network and synergizes with venetoclax in acute myeloid leukemia

Published:2022-03-07 Issue:4 Volume:14 Page:
ISSN:1757-4676
Container-title:EMBO Molecular Medicine
language:en
Short-container-title:EMBO Mol Med

Author:

He Lixiazi¹²,Arnold Christian²³,Thoma Judith⁴,Rohde Christian¹²,Kholmatov Maksim²³,Garg Swati¹²⁵,Hsiao Cheng‐Chih⁶,Viol Linda⁷⁸,Zhang Kaiqing⁹^ORCID,Sun Rui⁹,Schmidt Christina¹,Janssen Maike¹,MacRae Tara¹⁰,Huber Karin¹,Thiede Christian¹¹^ORCID,Hébert Josée¹²¹³¹⁴,Sauvageau Guy¹⁰¹³¹⁴,Spratte Julia¹⁵,Fluhr Herbert¹⁵,Aust Gabriela¹⁶,Müller‐Tidow Carsten¹²,Niehrs Christof⁹¹⁷,Pereira Gislene⁷⁸^ORCID,Hamann Jörg⁶^ORCID,Tanaka Motomu⁴¹⁸^ORCID,Zaugg Judith B²³^ORCID,Pabst Caroline¹²^ORCID

Affiliation:

1. Department of Medicine V, Hematology, Oncology and Rheumatology University Hospital Heidelberg Heidelberg Germany

2. Molecular Medicine Partnership Unit (MMPU) University of Heidelberg and European Molecular Biology Laboratory (EMBL) Heidelberg Germany

3. European Molecular Biology Laboratory (EMBL) Heidelberg Germany

4. Physical Chemistry of Biosystems Institute of Physical Chemistry Heidelberg University Heidelberg Germany

5. Department of Medical Oncology Dana Farber Cancer Institute Boston MA USA

6. Department of Experimental Immunology Amsterdam Infection & Immunity Institute Amsterdam University Medical Centers Amsterdam Netherlands

7. Centre for Organismal Studies (COS)/Centre for Cell and Molecular Biology (ZMBH) University of Heidelberg Heidelberg Germany

8. German Cancer Research Centre (DKFZ) DKFZ‐ZMBH Alliance Heidelberg Germany

9. Division of Molecular Embryology DKFZ‐ZMBH Alliance Heidelberg Germany

10. Laboratory of Molecular Genetics of Stem Cells Institute for Research in Immunology and Cancer University of Montreal Montreal Quebec Canada

11. Department of Internal Medicine I University Hospital of Dresden Carl Gustav Carus Dresden Germany

12. The Quebec Leukemia Cell Bank and Division of Hematology‐Oncology Maisonneuve‐Rosemont Hospital Montréal Canada

13. Department of Medicine Faculty of Medicine Université de Montréal Montréal Canada

14. Division of Hematology‐Oncology Maisonneuve‐Rosemont Hospital Montreal Quebec Canada

15. Department of Gynecology and Obstetrics University Hospital Heidelberg Heidelberg Germany

16. Department of Surgery Research Laboratories Leipzig University Leipzig Germany

17. Institute of Molecular Biology (IMB) Mainz Germany

18. Center for Integrative Medicine and Physics Institute for Advanced Study Kyoto University Kyoto Japan

Funder

Deutsche Krebshilfe

Deutsche Forschungsgemeinschaft

Publisher

EMBO

Subject

Molecular Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.15252/emmm.202114990

Reference91 articles.

1. Subtype-specific regulatory network rewiring in acute myeloid leukemia

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5. THE TOXICITY OF POISONS APPLIED JOINTLY1

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