A dual‐AAV approach restores fast exocytosis and partially rescues auditory function in deaf otoferlin knock‐out mice-Reference-Cited by-同舟云学术

A dual‐AAV approach restores fast exocytosis and partially rescues auditory function in deaf otoferlin knock‐out mice

Published:2018-12-03 Issue:1 Volume:11 Page:
ISSN:1757-4676
Container-title:EMBO Molecular Medicine
language:en
Short-container-title:EMBO Mol Med

Author:

Al‐Moyed Hanan¹²,Cepeda Andreia P¹²^ORCID,Jung SangYong³⁴,Moser Tobias²³⁴^ORCID,Kügler Sebastian⁵^ORCID,Reisinger Ellen¹^ORCID

Affiliation:

1. Molecular Biology of Cochlear Neurotransmission Group Department of Otorhinolaryngology University Medical Center Göttingen, and Collaborative Research Center 889 University of Göttingen Göttingen Germany

2. Göttingen Graduate School for Neurosciences, Biophysics, and Molecular Biosciences University of Göttingen Göttingen Germany

3. Institute for Auditory Neurosciences and InnerEarLab University Medical Center Göttingen Göttingen Germany

4. Synaptic Nanophysiology Group Max Planck Institute for Biophysical Chemistry Göttingen Germany

5. Center Nanoscale Microscopy and Physiology of the Brain (CNMPB) Department of Neurology University Medical Center Göttingen Göttingen Germany

Funder

Deutsche Forschungsgemeinschaft

Publisher

EMBO

Subject

Molecular Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.15252/emmm.201809396

Reference55 articles.

1. Restoration of Hearing in the VGLUT3 Knockout Mouse Using Virally Mediated Gene Therapy

2. In Vivo Delivery of Recombinant Viruses to the Fetal Murine Cochlea: Transduction Characteristics and Long-Term Effects on Auditory Function

3. Calcium- and Otoferlin-Dependent Exocytosis by Immature Outer Hair Cells

4. Contribution of auditory nerve fibers to compound action potential of the auditory nerve

5. Onset Coding Is Degraded in Auditory Nerve Fibers from Mutant Mice Lacking Synaptic Ribbons

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