TIP 30 counteracts cardiac hypertrophy and failure by inhibiting translational elongation

Author:

Grund Andrea12,Szaroszyk Malgorzata1,Korf‐Klingebiel Mortimer1,Malek Mohammadi Mona12,Trogisch Felix A2,Schrameck Ulrike1,Gigina Anna1,Tiedje Christopher3ORCID,Gaestel Matthias3ORCID,Kraft Theresia4,Hegermann Jan5,Batkai Sandor6,Thum Thomas67,Perrot Andreas8,Remedios Cris dos9,Riechert Eva10,Völkers Mirko1011ORCID,Doroudgar Shirin1011,Jungmann Andreas10,Bauer Ralf10,Yin Xiaoke12,Mayr Manuel12,Wollert Kai C17,Pich Andreas13,Xiao Hua14,Katus Hugo A1011,Bauersachs Johann17,Müller Oliver J101115,Heineke Joerg12711ORCID

Affiliation:

1. Department for Cardiology and Angiology Hannover Medical School Hannover Germany

2. Department of Cardiovascular Research European Center for Angioscience (ECAS) Medical Faculty Mannheim University of Heidelberg Mannheim Germany

3. Institute of Cell Biochemistry Hannover Medical School Hannover Germany

4. Institute for Molecular and Cellphysiology Hannover Medical School Hannover Germany

5. Research Core Unit Electron Microscopy Hannover Medical School Hannover Germany

6. Institute of Molecular and Translational Therapeutic Strategies (IMTTS) Hannover Medical School Hannover Germany

7. Cluster of Excellence Rebirth Hannover Medical School Hannover Germany

8. Experimental and Clinical Research Center A Joint Cooperation of Max‐Delbrück Center for Molecular Medicine and Charité‐Universitätsmedizin Berlin Berlin Germany

9. Sydney Heart Bank University of Sydney Sydney NSW Australia

10. Department of Cardiology, Angiology and Pneumology Medical Faculty of Heidelberg University of Heidelberg Heidelberg Germany

11. DZHK (German Centre for Cardiovascular Research) Partner Site Heidelberg/Mannheim Heidelberg Germany

12. King's British Heart Foundation Centre King's College London London UK

13. Core Unit Proteomics Hannover Medical School Hannover Germany

14. Department of Physiology Michigan State University East Lansing MI USA

15. Department of Internal Medicine III, Cardiology, Angiology and Intensive Care Medicine Universitätsklinikum Schleswig‐Holstein Kiel Germany

Funder

Deutsche Forschungsgemeinschaft

H2020 European Research Council

European Commission

Baden-Württemberg Stiftung

Bundesministerium für Bildung und Forschung

Deutsches Zentrum für Herz-Kreislaufforschung

Publisher

EMBO

Subject

Molecular Medicine

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