Stop wasting protein—Proteasome inhibition to target diseases linked to mitochondrial import
Author:
Affiliation:
1. Department of Chemistry Institute for Biochemistry University of Cologne Cologne Germany
Funder
Deutsche Forschungsgemeinschaft
Publisher
EMBO
Subject
Molecular Medicine
Link
https://onlinelibrary.wiley.com/doi/pdf/10.15252/emmm.201910441
Reference11 articles.
1. The Ubiquitin-Proteasome System Regulates Mitochondrial Intermembrane Space Proteins
2. Retro-translocation of mitochondrial intermembrane space proteins
3. Mutations in the accessory subunit NDUFB10 result in isolated complex I deficiency and illustrate the critical role of intermembrane space import for complex I holoenzyme assembly;Friederich MW;Hum Mol Genet,2017
4. Vectorial Import via a Metastable Disulfide-Linked Complex Allows for a Quality Control Step and Import by the Mitochondrial Disulfide Relay
5. Cysteine residues in mitochondrial intermembrane space proteins: more than just import
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