Inhibiting MARSs reduces hyperhomocysteinemia‐associated neural tube and congenital heart defects

Author:

Mei Xinyu1234ORCID,Qi Dashi15,Zhang Ting16,Zhao Ying127,Jin Li12,Hou Junli8,Wang Jianhua6,Lin Yan124,Xue Yu9ORCID,Zhu Pingping8,Liu Zexian9ORCID,Huang Lei12,Nie Ji12,Si Wen8,Ma Jingyi10,Ye Jianhong12,Finnell Richard H11ORCID,Saiyin Hexige1,Wang Hongyan12ORCID,Zhao Jianyuan124,Zhao Shimin124ORCID,Xu Wei124ORCID

Affiliation:

1. State Key Lab of Genetic Engineering School of Life Sciences and Institutes of Biomedical Sciences Obstetrics & Gynecology Hospital of Fudan University Shanghai China

2. NHC Key Lab of Reproduction Regulation (Shanghai Institute of Planned Parenthood Research) Shanghai China

3. Interdisciplinary Research Center on Biology and Chemistry Shanghai Institute of Organic Chemistry Chinese Academy of Sciences Shanghai China

4. Collaborative Innovation Center for Biotherapy West China Hospital Sichuan University Chengdu China

5. Shanghai Key Lab of Birth Defect Children's Hospital of Fudan University Shanghai China

6. Capital Institute of Pediatrics Beijing China

7. Shanghai Laboratory Animal Research Center Shanghai China

8. Department of Chemistry Fudan University Shanghai China

9. Department of Medical Engineering College of Life Sciences and Technology Huazhong University of Science and Technology Wuhan China

10. Ludwig Institute for Cancer Research Nuffield Department of Clinical Medicine University of Oxford Oxford UK

11. Center for Precision Environmental Health Departments of Molecular and Human Genetics, Molecular & Cellular Biology and Medicine Baylor College of Medicine Houston TX USA

Funder

Foundation for Innovative Research Groups of the National Natural Science Foundation of China

Publisher

EMBO

Subject

Molecular Medicine

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