Immune‐mediated ECM depletion improves tumour perfusion and payload delivery

Author:

Yeow Yen Ling1,Kotamraju Venkata Ramana2,Wang Xiao1,Chopra Meenu1,Azme Nasibah1,Wu Jiansha1,Schoep Tobias D3,Delaney Derek S1ORCID,Feindel Kirk4,Li Ji1,Kennedy Kelsey M5,Allen Wes M15,Kennedy Brendan F15,Larma Irma4,Sampson David D45,Mahakian Lisa M6,Fite Brett Z6,Zhang Hua6,Friman Tomas2,Mann Aman P2,Aziz Farah A7,Kumarasinghe M Priyanthi8,Johansson Mikael7,Ee Hooi C7,Yeoh George1,Mou Lingjun7,Ferrara Katherine W6,Billiran Hector2,Ganss Ruth1,Ruoslahti Erkki2,Hamzah Juliana1ORCID

Affiliation:

1. Harry Perkins Institute of Medical Research Centre for Medical Research QEII Medical Centre The University of Western Australia Perth WA Australia

2. Cancer Research Center Sanford Burnham Prebys Medical Discovery Institute La Jolla CA USA

3. Telethon Kids Institute Subiaco WA Australia

4. Centre for Microscopy, Characterisation & Analysis The University of Western Australia Perth WA Australia

5. Department of Electrical, Electronic & Computer Engineering School of Engineering The University of Western Australia Perth WA Australia

6. Department of Biomedical Engineering University of California Davis Davis CA USA

7. Sir Charles Gairdner Hospital Perth WA Australia

8. PathWest Laboratory Medicine QE2 Medical Centre Perth WA Australia

Funder

National Health and Medical Research Council

Center for Strategic Scientific Initiatives, National Cancer Institute

National Cancer Institute

Cancer Council Western Australia

Publisher

EMBO

Subject

Molecular Medicine

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