Single‐cell transcriptomics reveals a senescence‐associated<scp>IL</scp>‐6/<scp>CCR6</scp>axis driving radiodermatitis-Reference-Cited by-同舟云学术

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Single‐cell transcriptomics reveals a senescence‐associatedIL‐6/CCR6axis driving radiodermatitis

Published:2022-07-04 Issue:8 Volume:14 Page:
ISSN:1757-4676
Container-title:EMBO Molecular Medicine
language:en
Short-container-title:EMBO Mol Med

Author:

Paldor Mor¹^ORCID,Levkovitch‐Siany Orr¹^ORCID,Eidelshtein Dana¹,Adar Revital¹,Enk Claes D²,Marmary Yitzhak¹,Elgavish Sharona³,Nevo Yuval³,Benyamini Hadar³,Plaschkes Inbar³,Klein Shiri¹,Mali Alex⁴,Rose‐John Stefan⁵^ORCID,Peled Amnon¹,Galun Eithan¹^ORCID,Axelrod Jonathan H¹^ORCID

Affiliation:

1. The Goldyne‐Savad Institute of Gene Therapy Hadassah Hebrew University Hospital Jerusalem Israel

2. Department of Dermatology Hadassah Hebrew University Hospital Jerusalem Israel

3. Info‐CORE, Bioinformatics Unit of the I‐CORE Hebrew University of Jerusalem Jerusalem Israel

4. Department of Pathology Hadassah Hebrew University Hospital Jerusalem Israel

5. Institut für Biochemie Christian‐Albrechts‐Universität zu Kiel Kiel Germany

Funder

Deutsche Forschungsgemeinschaft

Israel Science Foundation

Publisher

EMBO

Subject

Molecular Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.15252/emmm.202115653

Reference96 articles.

1. IL‐17 is produced by nickel‐specific T lymphocytes and regulates ICAM‐1 expression and chemokine production in human keratinocytes: synergistic or antagonist effects with IFN‐gamma and TNF‐alpha;Albanesi C;J Immunol,1999

2. Senolytic CAR T cells reverse senescence-associated pathologies

3. Dimensionality reduction for visualizing single-cell data using UMAP

4. Acute and chronic radiation injury

5. Toll-like Receptor 5 Agonist Protects Mice From Dermatitis and Oral Mucositis Caused by Local Radiation: Implications for Head-and-Neck Cancer Radiotherapy

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