Disease modification and symptom relief in osteoarthritis using a mutated <scp>GCP</scp> ‐2/ <scp>CXCL6</scp> chemokine-Reference-Cited by-同舟云学术

Disease modification and symptom relief in osteoarthritis using a mutated GCP ‐2/ CXCL6 chemokine

Published:2022-12-12 Issue:1 Volume:15 Page:
ISSN:1757-4676
Container-title:EMBO Molecular Medicine
language:en
Short-container-title:EMBO Mol Med

Author:

Caxaria Sara¹,Kouvatsos Nikolaos²^ORCID,Eldridge Suzanne E¹,Alvarez‐Fallas Mario¹^ORCID,Thorup Anne‐Sophie¹,Cici Daniela³^ORCID,Barawi Aida¹,Arshed Ammaarah¹,Strachan Danielle¹^ORCID,Carletti Giulia¹,Huang Xinying¹,Bharde Sabah¹,Deniz Melody¹,Wilson Jacob¹^ORCID,Thomas Bethan L¹,Pitzalis Costantino¹,Cantatore Francesco Paolo³,Sayilekshmy Manasi¹,Sikandar Shafaq¹^ORCID,Luyten Frank P⁴^ORCID,Pap Thomas⁵^ORCID,Sherwood Joanna C⁵^ORCID,Day Anthony J²⁶^ORCID,Dell'Accio Francesco¹^ORCID

Affiliation:

1. William Harvey Research Institute, Barts and the London School of Medicine and Dentistry Queen Mary University of London London UK

2. Wellcome Centre for Cell‐Matrix Research, Manchester Academic Health Science Centre University of Manchester Manchester UK

3. Rheumatology Clinic, Department of Medical and Surgical Sciences University of Foggia Foggia Italy

4. Department of Development and Regeneration, Skeletal Biology and Engineering Research Center KU Leuven Leuven Belgium

5. Institute of Musculoskeletal Medicine University Hospital Münster Münster Germany

6. Lydia Becker Institute of Immunology and Inflammation, Faculty of Biology, Medicine & Health, Manchester Academic Health Science Centre University of Manchester Manchester UK

Funder

Barts Charity

Deutsche Forschungsgemeinschaft

Foundation for Research in Rheumatology

Rosetrees Trust

Royal Society

Versus Arthritis

Publisher

EMBO

Subject

Molecular Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.15252/emmm.202216218

Reference54 articles.

1. Loss of NPP1 induces cartilage remodelling into bone and OA-like changes in mice

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3. ELR+ CXC chemokines and their receptors (CXC chemokine receptor 1 and CXC chemokine receptor 2) as new therapeutic targets

4. Inducible chondrocyte‐specific overexpression of BMP2 in young mice results in severe aggravation of osteophyte formation in experimental OA without altering cartilage damage;Blaney Davidson EN;Ann Rheum Dis,2014

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