A novel phosphocholine‐mimetic inhibits a pro‐inflammatory conformational change in C‐reactive protein

Author:

Zeller Johannes12ORCID,Cheung Tung Shing Karen S34ORCID,Nero Tracy L345ORCID,McFadyen James D24ORCID,Krippner Guy2ORCID,Bogner Balázs1,Kreuzaler Sheena1,Kiefer Jurij1ORCID,Horner Verena K1,Braig David1ORCID,Danish Habiba26,Baratchi Sara6ORCID,Fricke Mark1ORCID,Wang Xiaowei24ORCID,Kather Michel G7ORCID,Kammerer Bernd7ORCID,Woollard Kevin J8ORCID,Sharma Prerna2,Morton Craig J34ORCID,Pietersz Geoffrey24ORCID,Parker Michael W345ORCID,Peter Karlheinz24ORCID,Eisenhardt Steffen U1ORCID

Affiliation:

1. Department of Plastic and Hand Surgery, University of Freiburg Medical Centre Medical Faculty of the University of Freiburg Freiburg Germany

2. Baker Heart and Diabetes Institute Melbourne Vic. Australia

3. Department of Biochemistry and Pharmacology, Bio21 Molecular Science and Biotechnology Institute The University of Melbourne Parkville Vic. Australia

4. Department of Cardiometabolic Health The University of Melbourne Parkville Vic. Australia

5. ACRF Rational Drug Discovery Centre St. Vincent's Institute of Medical Research Fitzroy Vic. Australia

6. School of Health and Biomedical Sciences RMIT University Melbourne Vic. Australia

7. Centre for Integrative Signalling Analysis CISA University of Freiburg Freiburg Germany

8. Centre for Inflammatory Disease Imperial College London London UK

Funder

Australian Cancer Research Foundation

Deutsche Forschungsgemeinschaft

National Health and Medical Research Council

National Heart Foundation of Australia

Publisher

EMBO

Subject

Molecular Medicine

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