Early disruption of photoreceptor cell architecture and loss of vision in a humanized pig model of usher syndromes-Reference-Cited by-同舟云学术

Early disruption of photoreceptor cell architecture and loss of vision in a humanized pig model of usher syndromes

Published:2022-03-07 Issue:4 Volume:14 Page:
ISSN:1757-4676
Container-title:EMBO Molecular Medicine
language:en
Short-container-title:EMBO Mol Med

Author:

Grotz Sophia¹²,Schäfer Jessica³,Wunderlich Kirsten A³,Ellederova Zdenka⁴,Auch Hannah¹²,Bähr Andrea²⁵,Runa‐Vochozkova Petra⁵^ORCID,Fadl Janet¹³,Arnold Vanessa³,Ardan Taras⁴,Veith Miroslav⁶^ORCID,Santamaria Gianluca⁵,Dhom Georg¹²,Hitzl Wolfgang⁷^ORCID,Kessler Barbara¹²^ORCID,Eckardt Christian²⁵,Klein Joshua³,Brymova Anna⁴,Linnert Joshua³,Kurome Mayuko¹²,Zakharchenko Valeri¹²,Fischer Andrea⁸,Blutke Andreas⁹,Döring Anna⁸,Suchankova Stepanka¹⁰,Popelar Jiri¹⁰,Rodríguez‐Bocanegra Eduardo¹¹¹²,Dlugaiczyk Julia¹³,Straka Hans¹⁴,May‐Simera Helen¹⁵^ORCID,Wang Weiwei¹⁶^ORCID,Laugwitz Karl‐Ludwig⁵,Vandenberghe Luk H¹⁶,Wolf Eckhard¹²^ORCID,Nagel‐Wolfrum Kerstin³¹⁷,Peters Tobias¹¹¹²^ORCID,Motlik Jan⁴,Fischer M Dominik¹⁸¹⁹,Wolfrum Uwe³^ORCID,Klymiuk Nikolai²⁵^ORCID

Affiliation:

1. Chair of Molecular Animal Breeding and Biotechnology LMU Munich Munich Germany

2. Center for Innovative Medical Models LMU Munich Munich Germany

3. Institute of Molecular Physiology Molecular Cell Biology Johannes Gutenberg University (JGU) Mainz Germany

4. Institute of Animal Physiology and Genetics Czech Academy of Science Libechov Czech Republic

5. Large Animal Models in Cardiovascular Research Internal Medical Department I TU Munich Munich Germany

6. Ophthalmology Clinic University Hospital Kralovske Vinohrady Praha Czech Republic

7. Biostatistics and Data Science Paracelsus Medical University Salzburg Austria

8. Veterinary Faculty Small Animal Clinics LMU Munich Munich Germany

9. Institute of Experimental Genetics Helmholtz Center Munich Neuherberg Germany

10. Institute of Experimental Medicine Czech Academy of Science Prague Czech Republic

11. Centre for Ophthalmology University Eye Hospital University Hospital Tübingen Tübingen Germany

12. Institute for Ophthalmic Research Centre for Ophthalmology University Hospital Tübingen Tübingen Germany

13. Department of Otorhinolaryngology, Head and Neck Surgery University Hospital Zurich (USZ) University of Zurich Zurich Switzerland

14. Faculty of Biology LMU Munich Planegg Germany

15. Institute of Molecular Physiology Cilia Biology JGU Mainz Mainz Germany

16. Grousbeck Gene Therapy Center Mass Eye and Ear and Harvard Medical School Boston MA USA

17. Institute of Developmental Biology and Neurobiology Johannes Gutenberg University (JGU) Mainz Germany

18. Oxford Eye Hospital Oxford University NHS Foundation Trust Oxford UK

19. Nuffield Laboratory of Ophthalmology NDCN University of Oxford Oxford UK

Funder

Deutsche Forschungsgemeinschaft

Foundation Fighting Blindness

Publisher

EMBO

Subject

Molecular Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.15252/emmm.202114817

Reference98 articles.

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4. Behavioral Assessment of Vision in Pigs

5. Myosin VIIa, harmonin and cadherin 23, three Usher I gene products that cooperate to shape the sensory hair cell bundle

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