Bacterial lysis, autophagy and innate immune responses during adjunctive phage therapy in a child

Author:

Khatami Ameneh12ORCID,Lin Ruby C Y234ORCID,Petrovic‐Fabijan Aleksandra3ORCID,Alkalay‐Oren Sivan56,Almuzam Sulaiman1,Britton Philip N12,Brownstein Michael J7,Dao Quang8,Fackler Joe7,Hazan Ronen5,Horne Bri’Anna7,Nir‐Paz Ran6,Iredell Jonathan R239ORCID

Affiliation:

1. Department of Infectious Diseases and Microbiology The Children’s Hospital at Westmead Westmead NSW Australia

2. Sydney Medical School The University of Sydney Sydney NSW Australia

3. Centre for Infectious Diseases and Microbiology Westmead Institute for Medical Research Westmead NSW Australia

4. School of Medical Sciences University of New South Wales Sydney NSW Australia

5. Institute of Dental Sciences and School of Dental Medicine The Hebrew University Jerusalem Israel

6. Department of Clinical Microbiology and Infectious Diseases Hadassah‐Hebrew University Medical Center, and the Faculty of Medicine The Hebrew University Jerusalem Israel

7. Adaptive Phage Therapeutics Gaithersburg MD USA

8. Department of Orthopaedics The Children’s Hospital at Westmead Westmead NSW Australia

9. Westmead Hospital Western Sydney Local Health District Westmead NSW Australia

Funder

National Health and Medical Research Council

Publisher

EMBO

Subject

Molecular Medicine

Reference23 articles.

1. Bacteriophage prehistory

2. DolgalevI(2020)msigdbr: MSigDB Gene Sets for Multiple Organisms in a Tidy Data Format R package version 7.1.1 ed.https://igordot.github.io/msigdbr/

3. Effect of antibiotics on endotoxin release from gram-negative bacteria

4. The brain-specific factor FEZ1 is a determinant of neuronal susceptibility to HIV-1 infection

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