IKKβ is required for the formation of the NLRP3 inflammasome
Author:
Affiliation:
1. MRC Protein Phosphorylation and Ubiquitylation Unit University of Dundee Dundee UK
2. Dundee Imaging Facility and Division of Cell Signalling and Immunology School of Life Sciences University of Dundee Dundee UK
Funder
Medical Research Council
Tenovus
Publisher
EMBO
Subject
Genetics,Molecular Biology,Biochemistry
Link
https://onlinelibrary.wiley.com/doi/pdf/10.15252/embr.202050743
Reference53 articles.
1. Pathogen Recognition and Innate Immunity
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3. Inflammasomes: mechanism of assembly, regulation and signalling
4. Novel IKK inhibitors: β-carbolines
5. PtdIns4P on dispersed trans-Golgi network mediates NLRP3 inflammasome activation
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