BRCA 1 and BARD 1 mediate apoptotic resistance but not longevity upon mitochondrial stress in Caenorhabditis elegans

Author:

Torgovnick Alessandro123,Schiavi Alfonso14,Shaik Anjumara1,Kassahun Henok56,Maglioni Silvia1,Rea Shane L7,Johnson Thomas E8,Reinhardt Hans C2,Honnen Sebastian9,Schumacher Björn3ORCID,Nilsen Hilde56,Ventura Natascia14ORCID

Affiliation:

1. Leibniz Research Institute for Environmental Medicine (IUF) Düsseldorf Germany

2. Clinic I of Internal Medicine Center for Integrated Oncology Center for Molecular Medicine and the CECAD Research Center University of Cologne Cologne Germany

3. Medical Faculty Institute for Genome Stability in Aging and Disease CECAD Research Center University of Cologne Cologne Germany

4. Institute for Clinical Chemistry and Laboratory Diagnostic Medical Faculty Heinrich Heine University of Düsseldorf Düsseldorf Germany

5. Department of Clinical Molecular Biology University of Oslo Oslo Norway

6. Akershus University Akershus Norway

7. Department of Pathology University of Washington Seattle WA USA

8. Institute for Behavioral Genetics & Department of Integrative Physiology University of Colorado at Boulder Boulder CO USA

9. Medical Faculty Institute of Toxicology Heinrich Heine University of Düsseldorf Düsseldorf Germany

Funder

Associazione Italiana per la Ricerca sul Cancro

Deutsche Forschungsgemeinschaft

Publisher

EMBO

Subject

Genetics,Molecular Biology,Biochemistry

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