Chronic inflammation decreases HSC fitness by activating the druggable Jak/Stat3 signaling pathway

Author:

Grusanovic Srdjan123ORCID,Danek Petr1ORCID,Kuzmina Maria12ORCID,Adamcova Miroslava K13ORCID,Burocziova Monika1ORCID,Mikyskova Romana4ORCID,Vanickova Karolina12ORCID,Kosanovic Sladjana12ORCID,Pokorna Jana5,Reinis Milan4ORCID,Brdicka Tomas5ORCID,Alberich‐Jorda Meritxell13ORCID

Affiliation:

1. Department of Hemato‐Oncology Institute of Molecular Genetics of the Czech Academy of Sciences Prague Czech Republic

2. Faculty of Science Charles University Prague Czech Republic

3. Childhood Leukaemia Investigation Prague Department of Pediatric Haematology and Oncology 2nd Faculty of Medicine Charles University in Prague University Hospital Motol Prague Czech Republic

4. Department of Immunological and Tumor models Institute of Molecular Genetics of the Czech Academy of Sciences Prague Czech Republic

5. Department of Leukocyte signaling Institute of Molecular Genetics of the Czech Academy of Sciences Prague Czech Republic

Funder

Grantová Agentura, Univerzita Karlova

Agentura Pro Zdravotnický Výzkum České Republiky

HORIZON EUROPE Marie Sklodowska-Curie Actions

Grantová Agentura České Republiky

Publisher

EMBO

Subject

Genetics,Molecular Biology,Biochemistry

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