Sensing of mycobacterial arabinogalactan by galectin‐9 exacerbates mycobacterial infection

Author:

Wu Xiangyang1,Wu Yong2,Zheng Ruijuan1,Tang Fen1,Qin Lianhua1,Lai Detian1,Zhang Lu3,Chen Lingming4,Yan Bo5,Yang Hua1,Wang Yang1,Li Feifei2,Zhang Jinyu3,Wang Fei1,Wang Lin1,Cao Yajuan1,Ma Mingtong1,Liu Zhonghua1,Chen Jianxia1,Huang Xiaochen1,Wang Jie1,Jin Ruiliang1,Wang Peng6,Sun Qin6,Sha Wei6,Lyu Liangdong7,Moura‐Alves Pedro89ORCID,Dorhoi Anca810ORCID,Pei Gang8ORCID,Zhang Peng11,Chen Jiayu12,Gao Shaorong12,Randow Felix13ORCID,Zeng Gucheng4ORCID,Chen Chang11,Ye Xin‐Shan2ORCID,Kaufmann Stefan H E81415ORCID,Liu Haipeng181617ORCID,Ge Baoxue116

Affiliation:

1. Shanghai Key Lab of Tuberculosis Shanghai Pulmonary Hospital Tongji University School of Medicine Shanghai China

2. State Key Laboratory of Natural and Biomimetic Drugs School of Pharmaceutical Sciences Peking University Beijing China

3. State Key Laboratory of Genetic Engineering Institute of Genetics School of Life Science Fudan University Shanghai China

4. Department of Microbiology Key Laboratory for Tropical Diseases Control of the Ministry of Education Zhongshan School of Medicine Sun Yat‐sen University Guangzhou China

5. Shanghai Public Health Clinical Center Fudan University Shanghai China

6. Department of TB Shanghai Pulmonary Hospital Tongji University School of Medicine Shanghai China

7. Key Laboratory of Medical Molecular Virology of the Ministry of Education/Ministry of Health School of Basic Medical Sciences Fudan University Shanghai China

8. Department of Immunology Max Planck Institute for Infection Biology Berlin Germany

9. Ludwig Institute for Cancer Research Nuffield Department of Medicine University of Oxford Oxford UK

10. Institute of Immunology Friedrich‐Loeffler‐Institut Greifswald–Insel Riems Germany

11. Department of Thoracic Surgery Shanghai Pulmonary Hospital Tongji University School of Medicine Shanghai China

12. Clinical and Translational Research Center of Shanghai First Maternity and Infant Hospital Shanghai Key Laboratory of Signaling and Disease Research School of Life Sciences and Technology Tongji University Shanghai China

13. Division of Protein and Nucleic Acid Chemistry MRC Laboratory of Molecular Biology Cambridge UK

14. Hagler Institute for Advanced Study at Texas A&M University College Station TX USA

15. Max Planck Institute for Biophysical Chemistry Göttingen Germany

16. Clinical and Translational Research Center Shanghai Pulmonary Hospital Tongji University School of Medicine Shanghai China

17. Central Laboratory Shanghai Pulmonary Hospital Tongji University School of Medicine Shanghai China

Funder

National Natural Science Foundation of China

Shanghai Shuguang Program

Publisher

EMBO

Subject

Genetics,Molecular Biology,Biochemistry

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