NPC 1 enables cholesterol mobilization during long‐term potentiation that can be restored in Niemann–Pick disease type C by CYP 46A1 activation
Author:
Affiliation:
1. Department of Molecular Neuropathology Centro de Biología Molecular “Severo Ochoa” (CSIC‐UAM) Madrid Spain
2. Laboratoire de Biophotonique et Pharmacologie Faculté de Pharmacie Université de Strasbourg Illkirch France
Funder
Fundación Alicia Koplowitz
Publisher
EMBO
Subject
Genetics,Molecular Biology,Biochemistry
Link
https://onlinelibrary.wiley.com/doi/pdf/10.15252/embr.201948143
Reference53 articles.
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2. SNAREs are concentrated in cholesterol-dependent clusters that define docking and fusion sites for exocytosis
3. The metabolism of sphingomyelin. II. Evidence of an enzymatic deficiency in Niemann-Pick diseae.
4. Murine Model of Niemann-Pick C Disease: Mutation in a Cholesterol Homeostasis Gene
5. Niemann–Pick C1 Is a Late Endosome-Resident Protein That Transiently Associates with Lysosomes and the Trans-Golgi Network
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