<scp>TRIM50</scp> promotes <scp>NLRP3</scp> inflammasome activation by directly inducing <scp>NLRP3</scp> oligomerization-Reference-Cited by-同舟云学术

TRIM50 promotes NLRP3 inflammasome activation by directly inducing NLRP3 oligomerization

Published:2022-09-30 Issue:11 Volume:23 Page:
ISSN:1469-221X
Container-title:EMBO reports
language:en
Short-container-title:EMBO Reports

Author:

Lin Yueke¹²,Lv Xiaoting¹²,Sun Caiyu¹²^ORCID,Sun Yanlin³,Yang Min¹,Ma Dapeng¹,Jing Weiqiang⁴,Zhao Yunxue⁵,Cheng Yeping¹,Xuan Haocheng¹,Han Lihui¹²^ORCID

Affiliation:

1. Shandong Provincial Key Laboratory of Infection and Immunology, Department of Immunology, School of Basic Medical Sciences, Cheeloo College of Medicine Shandong University Jinan China

2. Shandong Provincial Clinical Research Center for Immune Diseases and Gout Jinan China

3. Department of Pathology, School of Basic Medical Sciences, Cheeloo College of Medicine Shandong University Jinan China

4. Department of Urology, Qilu Hospital, Cheeloo College of Medicine Shandong University Jinan China

5. Department of Pharmacology, School of Basic Medical Sciences, Cheeloo College of Medicine Shandong University Jinan China

Funder

National Natural Science Foundation of China

Publisher

EMBO

Subject

Genetics,Molecular Biology,Biochemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.15252/embr.202154569

Reference50 articles.

1. NLRP3 inflammasome in endothelial dysfunction

2. SUMO-mediated regulation of NLRP3 modulates inflammasome activity

3. Inflammasomes: mechanism of assembly, regulation and signalling

4. Mechanism of endophilin N-BAR domain-mediated membrane curvature

5. Prion-like Polymerization Underlies Signal Transduction in Antiviral Immune Defense and Inflammasome Activation

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