Inclusion of cGAMP within virus‐like particle vaccines enhances their immunogenicity

Author:

Chauveau Lise1ORCID,Bridgeman Anne1,Tan Tiong K1,Beveridge Ryan23,Frost Joe N1,Rijal Pramila1,Pedroza‐Pacheco Isabela4,Partridge Thomas4,Gilbert‐Jaramillo Javier56,Knight Michael L5,Liu Xu57,Russell Rebecca A5,Borrow Persephone4ORCID,Drakesmith Hal1,Townsend Alain R1,Rehwinkel Jan1ORCID

Affiliation:

1. Medical Research Council Human Immunology Unit Radcliffe Department of Medicine Medical Research Council Weatherall Institute of Molecular Medicine University of Oxford Oxford UK

2. MRC Molecular Hematology Unit MRC Weatherall Institute of Molecular Medicine John Radcliffe Hospital University of Oxford Oxford UK

3. Virus Screening Facility MRC Weatherall Institute of Molecular Medicine John Radcliffe Hospital University of Oxford Oxford UK

4. Nuffield Department of Clinical Medicine University of Oxford Oxford UK

5. Sir William Dunn School of Pathology University of Oxford Oxford UK

6. Department of Physiology, Anatomy and Genetics University of Oxford Oxford UK

7. Key Laboratory of Human Disease Comparative Medicine National Health Commission of China (NHC), Institute of Laboratory Animal Science Peking Union Medicine College Chinese Academy of Medical Sciences Beijing China

Funder

Division of Microbiology and Infectious Diseases, National Institute of Allergy and Infectious Diseases

Biotechnology and Biological Sciences Research Council

Publisher

EMBO

Subject

Genetics,Molecular Biology,Biochemistry

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