IL ‐21 has a critical role in establishing germinal centers by amplifying early B cell proliferation
Author:
Affiliation:
1. Department of Immunology and Pathology Monash University Melbourne Vic Australia
2. Immunology Division Garvan Institute of Medical Research Darlinghurst NSW Australia
3. St. Vincent's Clinical School UNSW Sydney Sydney NSW Australia
Funder
National Health and Medical Research Council
Monash University
Stavros Niarchos Foundation
Vardalinstitutet
Publisher
EMBO
Subject
Genetics,Molecular Biology,Biochemistry
Link
https://onlinelibrary.wiley.com/doi/pdf/10.15252/embr.202254677
Reference74 articles.
1. Second signals rescue B cells from activation-induced mitochondrial dysfunction and death
2. Imaging of Germinal Center Selection Events During Affinity Maturation
3. B cell–intrinsic signaling through IL-21 receptor and STAT3 is required for establishing long-lived antibody responses in humans
4. Defective TCR expression in transgenic mice constructed using cDNA-based α- and β-chain genes under the control of heterologous regulatory elements
5. The SWHEL System for High-Resolution Analysis of In Vivo Antigen-Specific T-Dependent B Cell Responses
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