<scp>ZBTB2</scp> links p53 deficiency to <scp>HIF</scp> ‐1‐mediated hypoxia signaling to promote cancer aggressiveness-Reference-Cited by-同舟云学术

ZBTB2 links p53 deficiency to HIF ‐1‐mediated hypoxia signaling to promote cancer aggressiveness

Published:2022-11-07 Issue:1 Volume:24 Page:
ISSN:1469-221X
Container-title:EMBO reports
language:en
Short-container-title:EMBO Reports

Author:

Koyasu Sho¹²³⁴^ORCID,Horita Shoichiro⁵^ORCID,Saito Keisuke⁴^ORCID,Kobayashi Minoru¹²^ORCID,Ishikita Hiroshi⁴^ORCID,Chow Christalle CT¹^ORCID,Kambe Gouki¹^ORCID,Nishikawa Shigeto⁶,Menju Toshi⁶^ORCID,Morinibu Akiyo¹²,Okochi Yasushi¹⁷^ORCID,Tabuchi Yoshiaki⁸^ORCID,Onodera Yasuhito⁹,Takeda Norihiko¹⁰,Date Hiroshi⁶,Semenza Gregg L¹¹¹²^ORCID,Hammond Ester M¹³^ORCID,Harada Hiroshi¹²^ORCID

Affiliation:

1. Laboratory of Cancer Cell Biology, Graduate School of Biostudies Kyoto University Kyoto Japan

2. Department of Genome Repair Dynamics, Radiation Biology Center, Graduate School of Biostudies Kyoto University Kyoto Japan

3. Department of Diagnostic Imaging and Nuclear Medicine, Graduate School of Medicine Kyoto University Kyoto Japan

4. Research Center for Advanced Science and Technology The University of Tokyo Tokyo Japan

5. Department of Bioregulation and Pharmacological Medicine Fukushima Medical University Fukushima Japan

6. Department of Thoracic Surgery, Graduate School of Medicine Kyoto University Kyoto Japan

7. Faculty of Medicine Kyoto University Kyoto Japan

8. Division of Molecular Genetics Research, Life Science Research Center University of Toyama Toyama Japan

9. Global Center for Biomedical Science and Engineering, Faculty of Medicine Hokkaido University Sapporo Japan

10. Division of Cardiology and Metabolism, Center for Molecular Medicine Jichi Medical University Tochigi Japan

11. McKusick‐Nathans Institute of Genetic Medicine Johns Hopkins University School of Medicine Baltimore Maryland USA

12. Institute for Cell Engineering Johns Hopkins University School of Medicine Baltimore Maryland USA

13. MRC Oxford Institute for Radiation Oncology, Department of Oncology University of Oxford Oxford UK

Funder

Foundation for Promotion of Cancer Research

Ichiro Kanehara Foundation for the Promotion of Medical Sciences and Medical Care

Japan Agency for Medical Research and Development

Kobayashi Foundation for Cancer Research

Princess Takamatsu Cancer Research Fund

Takeda Science Foundation

Uehara Memorial Foundation

Yasuda Memorial Medical Foundation

Publisher

EMBO

Subject

Genetics,Molecular Biology,Biochemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.15252/embr.202154042

Reference38 articles.

1. p53 mutants cooperate with HIF-1 in transcriptional regulation of extracellular matrix components to promote tumor progression

2. Chromosome 17 Deletions and p53 Gene Mutations in Colorectal Carcinomas

3. Requirement for p53 and p21 to Sustain G 2 Arrest After DNA Damage

4. Role of stanniocalcin‐1 in breast cancer;Chen F;Oncol Lett,2019

5. MDM2 Gene Amplification and Transcript Levels in Human Sarcomas: Relationship to TP53 Gene Status

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1. ZBTB7A forms a heterodimer with ZBTB2 and inhibits ZBTB2 homodimerization required for full activation of HIF-1;Biochemical and Biophysical Research Communications;2024-11

2. Cellular signaling in the hypoxic cancer microenvironment: Implications for drug resistance and therapeutic targeting;Cellular Signalling;2024-01

3. DDX5 enhances HIF‐1 activity by promoting the interaction of HIF‐1α with HIF‐1β and recruiting the resulting heterodimer to its target gene loci;Biology of the Cell;2023-12-19

4. ZBTB2 is Recruited to a Specific Subset of HIF-1 Target Loci to Facilitate Full Gene Expression Under Hypoxia;Journal of Molecular Biology;2023-08