Hsp90‐mediated regulation of DYRK3 couples stress granule disassembly and growth via mTORC1 signaling

Author:

Mediani Laura1,Antoniani Francesco1,Galli Veronica1,Vinet Jonathan12,Carrà Arianna Dorotea1,Bigi Ilaria1,Tripathy Vadreenath3,Tiago Tatiana1,Cimino Marco1,Leo Giuseppina1,Amen Triana4ORCID,Kaganovich Daniel4ORCID,Cereda Cristina2ORCID,Pansarasa Orietta2,Mandrioli Jessica5,Tripathi Priyanka6,Troost Dirk7,Aronica Eleonora7,Buchner Johannes8ORCID,Goswami Anand6,Sterneckert Jared3,Alberti Simon9ORCID,Carra Serena1ORCID

Affiliation:

1. Department of Biomedical, Metabolic and Neural Sciences Centre for Neuroscience and Nanotechnology University of Modena and Reggio Emilia Modena Italy

2. Genomic and Post‐Genomic Center IRCCS Mondino Foundation Pavia Italy

3. Center for Regenerative Therapies TU Dresden Technische Universität Dresden Dresden Germany

4. Department of Experimental Neurodegeneration University Medical Center Göttingen Göttingen Germany

5. Department of Neuroscience St. Agostino Estense HospitalAzienda Ospedaliero Universitaria di Modena Modena Italy

6. Institute of Neuropathology RWTH Aachen University Hospital Aachen Germany

7. Department of (Neuro)Pathology Amsterdam Neuroscience Amsterdam UMCUniversity of Amsterdam Amsterdam The Netherlands

8. Center for Integrated Protein Science Munich at the Department Chemie Technische Universität München Garching Germany

9. Biotechnology Center (BIOTEC) Center for Molecular and Cellular Bioengineering (CMCB) Technische Universität Dresden Dresden Germany

Funder

Fondazione Italiana di Ricerca per la Sclerosi Laterale Amiotrofica

Ministero degli Affari Esteri e della Cooperazione Internazionale

EU Joint Programme – Neurodegenerative Disease Research

Fondazione Cariplo

Ministero dell’Istruzione, dell’Università e della Ricerca

Deutsche Forschungsgemeinschaft

H2020 European Research Council

Publisher

EMBO

Subject

Genetics,Molecular Biology,Biochemistry

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