Transforming primary human hepatocytes into hepatocellular carcinoma with genetically defined factors

Author:

Jiang Zhiwu1,Cheng Lin2,Wu Zhiping1,Zhou Linfu1,Wang Haitao3ORCID,Hong Qilan2,Wu Qiting1,Long Youguo1,Huang Yunlin1,Xu Gaoqi2,Yao Yao1,Tang Zhaoyang4,Zhang Zhenfeng5ORCID,Yang Lili6,Luo Wei7,Yang Jie8,Gong Likun9,Liu Pentao10,Chen Xinwen1,Cui Shuzhong11,Zhang Qi12,Li Yinxiong1ORCID,Li Peng1213ORCID

Affiliation:

1. China‐New Zealand Joint Laboratory on Biomedicine and Health, State Key Laboratory of Respiratory Disease, Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, Center for Cell Regeneration and Biological Therapies, Guangzhou Institutes of Biomedicine and Health Chinese Academy of Sciences Guangzhou China

2. Bioland Laboratory (Guangzhou Regenerative Medicine and Health Guangdong Laboratory) Guangzhou China

3. Cancer Center Faculty of Health Sciences University of Macau Macau China

4. Hunan Zhaotai Biomedicine Co. Ltd. Changsha China

5. The Second Affiliated Hospital of Guangzhou Medical University Guangzhou China

6. Department of Nutrition Guangdong Provincial Key Laboratory of Food School of Public Health Sun Yat‐sen University Guangzhou China

7. Clinical Research Institute The First People's Hospital of Foshan Foshan Guangdong China

8. Guangdong Women and Children Hospital Panyu, Guangzhou China

9. Shanghai Institute of Materia Medica Chinese Academy of Sciences, Zhang Jiang Hi‐Tech Park Shanghai China

10. School of Biomedical Sciences, Stem Cell, and Regenerative Medicine Consortium Li Ka Shing Faculty of Medicine The University of Hong Kong Hong Kong China

11. Cancer Hospital and Institute of Guangzhou Medical University Guangzhou China

12. Guangdong Key Laboratory of Liver Disease Research The Third Affiliated Hospital of Sun Yat‐sen University Guangzhou China

13. Centre for Regenerative Medicine and Health Hong Kong Institute of Science & Innovation Chinese Academy of Sciences Hong Kong China

Funder

National Key Research and Development Program of China

National Natural Science Foundation of China

Publisher

EMBO

Subject

Genetics,Molecular Biology,Biochemistry

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