Fusion of lysosomes with secretory organelles leads to uncontrolled exocytosis in the lysosomal storage disease mucolipidosis type IV

Author:

Park Soonhong12,Ahuja Malini1,Kim Min Seuk3,Brailoiu G Cristina4,Jha Archana1,Zeng Mei1,Baydyuk Maryna5,Wu Ling‐Gang5,Wassif Christopher A6,Porter Forbes D6,Zerfas Patricia M7,Eckhaus Michael A7,Brailoiu Eugen8,Shin Dong Min2,Muallem Shmuel1

Affiliation:

1. Epithelial Signaling and Transport Section Molecular Physiology and Therapeutics Branch NIDCR NIH Bethesda MD USA

2. Department of Oral Biology BK 21 PLUS Project Yonsei University College of Dentistry Seoul Korea

3. Department of Oral Physiology School of Dentistry Wonkwang University Iksan City Korea

4. Department of Pharmaceutical Sciences Jefferson School of Pharmacy Thomas Jefferson University Philadelphia PA USA

5. National Institute of Neurological Disorders and Stroke Bethesda MD USA

6. Program on Developmental Endocrinology and Genetics Eunice Kennedy Shriver National Institute of Child Health and Human Development National Institutes of Health Bethesda MD USA

7. Diagnostic and Research Services Branch Division of Veterinary Resources Office of Research Services National Institutes of Health Bethesda MD USA

8. Department of Pharmacology Temple University School of Medicine Philadelphia PA USA

Funder

National Institutes of Health Grants

Center for Substance Abuse Research

Temple University

NIH/NIDCR

Intramural Research Program of NICHD

National Research Foundation of Korea (NRF)

NRF

Korea Government

Publisher

EMBO

Subject

Genetics,Molecular Biology,Biochemistry

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