Regulation and inhibition of the DNA sensor cGAS-Reference-Cited by-同舟云学术

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Regulation and inhibition of the DNA sensor cGAS

Published:2020-11-05 Issue:12 Volume:21 Page:
ISSN:1469-221X
Container-title:EMBO reports
language:en
Short-container-title:EMBO Reports

Author:

Hertzog Jonny¹^ORCID,Rehwinkel Jan¹^ORCID

Affiliation:

1. MRC Human Immunology Unit MRC Weatherall Institute of Molecular Medicine Radcliffe Department of Medicine University of Oxford Oxford UK

Funder

Medical Research Council

Publisher

EMBO

Subject

Genetics,Molecular Biology,Biochemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.15252/embr.202051345

Reference241 articles.

1. STING Recognition of Cytoplasmic DNA Instigates Cellular Defense

2. cGAS produces a 2′-5′-linked cyclic dinucleotide second messenger that activates STING

3. Cell intrinsic immunity spreads to bystander cells via the intercellular transfer of cGAMP

4. TREX1 Deficiency Triggers Cell-Autonomous Immunity in a cGAS-Dependent Manner

5. cGAS in action: Expanding roles in immunity and inflammation

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1. Targeting activation of cGAS-STING signaling pathway by engineered biomaterials for enhancing cancer immunotherapy;Materials Today;2024-09

2. Mononuclear Phagocytes, Cellular Immunity, and Nobel Prizes: A Historic Perspective;Cells;2024-08-19

3. TRIM35 Negatively Regulates the cGAS-STING-Mediated Signaling Pathway by Attenuating K63-Linked Ubiquitination of STING;Inflammation;2024-08-01

4. The role of cGAS in epithelial dysregulation in inflammatory bowel disease and gastrointestinal malignancies;Frontiers in Pharmacology;2024-07-10

5. The roles of nuclear orphan receptor NR2F6 in anti-viral innate immunity;PLOS Pathogens;2024-06-03

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