Mechanism and inhibition of the papain‐like protease, PLpro, of SARS‐CoV‐2-Reference-Cited by-同舟云学术

Mechanism and inhibition of the papain‐like protease, PLpro, of SARS‐CoV‐2

Published:2020-08-26 Issue:18 Volume:39 Page:
ISSN:0261-4189
Container-title:The EMBO Journal
language:en
Short-container-title:EMBO J

Author:

Klemm Theresa¹^ORCID,Ebert Gregor¹,Calleja Dale J¹^ORCID,Allison Cody C¹,Richardson Lachlan W¹^ORCID,Bernardini Jonathan P¹²^ORCID,Lu Bernadine GC¹^ORCID,Kuchel Nathan W¹,Grohmann Christoph¹,Shibata Yuri¹,Gan Zhong Yan¹^ORCID,Cooney James P¹^ORCID,Doerflinger Marcel¹^ORCID,Au Amanda E¹^ORCID,Blackmore Timothy R¹^ORCID,Heden van Noort Gerbrand J³^ORCID,Geurink Paul P³,Ovaa Huib³,Newman Janet⁴^ORCID,Riboldi‐Tunnicliffe Alan⁵^ORCID,Czabotar Peter E¹,Mitchell Jeffrey P¹,Feltham Rebecca¹,Lechtenberg Bernhard C¹^ORCID,Lowes Kym N¹,Dewson Grant¹^ORCID,Pellegrini Marc¹^ORCID,Lessene Guillaume¹⁶^ORCID,Komander David¹^ORCID

Affiliation:

1. The Walter and Eliza Hall Institute of Medical Research and Department of Medical Biology University of Melbourne Melbourne Vic. Australia

2. Department of Biochemistry and Molecular Biology Michael Smith Laboratories University of British Columbia Vancouver BC Canada

3. Oncode Institute and Department of Cell and Chemical Biology Leiden University Medical Centre Leiden The Netherlands

4. Commonwealth Scientific and Industrial Research Organisation (CSIRO) Biomedical Program Parkville Vic. Australia

5. Australian Synchrotron ANSTO Clayton Vic. Australia

6. Pharmacology and Therapeutics Department University of Melbourne Melbourne Vic. Australia

Funder

National Health and Medical Research Council

Nederlandse Organisatie voor Wetenschappelijk Onderzoek

Publisher

EMBO

Subject

General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,Molecular Biology,General Neuroscience

Link

https://onlinelibrary.wiley.com/doi/pdf/10.15252/embj.2020106275

Reference70 articles.

1. The Phenix software for automated determination of macromolecular structures

2. Molecular basis for ubiquitin and ISG15 cross-reactivity in viral ovarian tumor domains

3. MX2: a high-flux undulator microfocus beamline serving both the chemical and macromolecular crystallography communities at the Australian Synchrotron

4. X-ray Structural and Biological Evaluation of a Series of Potent and Highly Selective Inhibitors of Human Coronavirus Papain-like Proteases

5. The SARS-coronavirus papain-like protease: Structure, function and inhibition by designed antiviral compounds

Cited by 346 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Viola stocksii: A rich source of antioxidant and anti-inflammatory flavonoid glycosides with converged therapeutic potential against SARS-CoV-2 MPro, spike trimer, and surface glycoproteins;Food Bioscience;2024-12

2. Disrupting protease and deubiquitinase activities of SARS-CoV-2 papain-like protease by natural and synthetic products discovered through multiple computational and biochemical approaches;International Journal of Biological Macromolecules;2024-10

3. Unraveling the structural and functional dimensions of SARS-CoV2 proteins in the context of COVID-19 pathogenesis and therapeutics;International Journal of Biological Macromolecules;2024-10

4. SARS-CoV-2 Genotyping Highlights the Challenges in Spike Protein Drift Independent of Other Essential Proteins;Microorganisms;2024-09-09

5. Development of novel antivrial agents that induce the degradation of the main protease of human-infecting coronaviruses;European Journal of Medicinal Chemistry;2024-09