hnRNPLL controls pluripotency exit of embryonic stem cells by modulating alternative splicing of Tbx3 and Bptf-Reference-Cited by-同舟云学术

hnRNPLL controls pluripotency exit of embryonic stem cells by modulating alternative splicing of Tbx3 and Bptf

Published:2020-12-22 Issue:4 Volume:40 Page:
ISSN:0261-4189
Container-title:The EMBO Journal
language:en
Short-container-title:The EMBO Journal

Author:

Wang Xue¹²,Ping Changyun¹³,Tan Puwen⁴,Sun Chenguang¹³,Liu Guang¹²,Liu Tao¹⁵,Yang Shuchun¹²,Si Yanmin¹³,Zhao Lijun¹³,Hu Yongfei⁴,Jia Yuyan¹²,Wang Xiaoshuang¹³,Zhang Meili¹²,Wang Fang¹³,Wang Dong⁴⁶⁷^ORCID,Yu Jia¹³^ORCID,Ma Yanni¹³^ORCID,Huang Yue¹²^ORCID

Affiliation:

1. State Key Laboratory of Medical Molecular Biology Institute of Basic Medical Sciences Chinese Academy of Medical SciencesSchool of Basic Medicine Peking Union Medical College Beijing China

2. Department of Medical Genetics Institute of Basic Medical Sciences Chinese Academy of Medical SciencesSchool of Basic Medicine Peking Union Medical College Beijing China

3. Key Laboratory of RNA Regulation and Hematopoiesis Department of Biochemistry and Molecular Biology Institute of Basic Medical Sciences Chinese Academy of Medical SciencesSchool of Basic Medicine Peking Union Medical College Beijing China

4. Department of Bioinformatics School of Basic Medical Sciences Southern Medical University Guangzhou China

5. Department of Obstetrics and Gynecology The Third Affiliated Hospital of Chongqing Medical University (General Hospital) Chongqing China

6. Dermatology Hospital Southern Medical University Guangzhou China

7. Center for Informational Biology University of Electronic Science and Technology of China Chengdu China

Funder

National Key Research and Development Program of China Stem Cell and Translational Research

National Natural Science Foundation of China

Publisher

EMBO

Subject

General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,Molecular Biology,General Neuroscience

Link

https://onlinelibrary.wiley.com/doi/pdf/10.15252/embj.2020104729

Reference74 articles.

1. AlexanderJ WamstadJ(2013)Gene Expression OmnibusGSE47948(https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE47948) [DATASET]

2. Exit from Pluripotency Is Gated by Intracellular Redistribution of the bHLH Transcription Factor Tfe3

3. Trim71 cooperates with microRNAs to repress Cdkn1a expression and promote embryonic stem cell proliferation

4. Alternative splicing in cancer: implications for biology and therapy

5. Alternative splicing: An important mechanism in stem cell biology

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