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Proteostatic imbalance and protein spreading in amyotrophic lateral sclerosis

Published:2021-03-31 Issue:10 Volume:40 Page:
ISSN:0261-4189
Container-title:The EMBO Journal
language:en
Short-container-title:EMBO J

Author:

Cicardi Maria Elena¹,Marrone Lara²,Azzouz Mimoun²,Trotti Davide¹^ORCID

Affiliation:

1. Department of Neuroscience Weinberg ALS Center Vickie and Jack Farber Institute for Neuroscience Thomas Jefferson University Philadelphia PA USA

2. Department of Neuroscience Sheffield Institute for Translational Neuroscience (SITraN) University of Sheffield Sheffield UK

Funder

National Institute on Aging

Muscular Dystrophy Association

U.S. Department of Defense

Publisher

EMBO

Subject

General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,Molecular Biology,General Neuroscience

Link

https://onlinelibrary.wiley.com/doi/pdf/10.15252/embj.2020106389

Reference434 articles.

1. Autophagy regulates exosomal release of prions in neuronal cells

2. Tunneling nanotubes: A possible highway in the spreading of tau and other prion-like proteins in neurodegenerative diseases

3. Frontal lobe dysfunction in amyotrophic lateral sclerosis

4. The Overlapping Genetics of Amyotrophic Lateral Sclerosis and Frontotemporal Dementia

5. Functional and dynamic polymerization of the ALS-linked protein TDP-43 antagonizes its pathologic aggregation

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1. Identification of potential drug targets for amyotrophic lateral sclerosis by Mendelian randomization analysis based on brain and plasma proteomics;Experimental Gerontology;2024-10

2. The prion-like effect and prion-like protein targeting strategy in amyotrophic lateral sclerosis;Heliyon;2024-08

3. Quantitative proteomics unveils known and previously unrecognized alterations in neuropathic nerves;Journal of Neurochemistry;2024-07-29

4. The Ile35 Residue of the ALS-Associated Mutant SOD1 Plays a Crucial Role in the Intracellular Aggregation of the Molecule;Molecular Neurobiology;2024-07-26

5. Extracellular Vesicles: The Next Generation of Biomarkers and Treatment for Central Nervous System Diseases;International Journal of Molecular Sciences;2024-07-05

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