Oxidative stress‐induced phosphorylation of <scp>JIP4</scp> regulates lysosomal positioning in coordination with <scp>TRPML1</scp> and <scp>ALG2</scp>-Reference-Cited by-同舟云学术

Oxidative stress‐induced phosphorylation of JIP4 regulates lysosomal positioning in coordination with TRPML1 and ALG2

Published:2022-10-11 Issue:22 Volume:41 Page:
ISSN:0261-4189
Container-title:The EMBO Journal
language:en
Short-container-title:The EMBO Journal

Author:

Sasazawa Yukiko¹²^ORCID,Souma Sanae³,Furuya Norihiko²³^ORCID,Miura Yoshiki⁴,Kazuno Saiko⁴,Kakuta Soichiro⁴,Suzuki Ayami³,Hashimoto Ryota⁴,Hirawake‐Mogi Hiroko³,Date Yuki³⁵,Imoto Masaya²,Ueno Takashi⁴,Kataura Tetsushi⁶^ORCID,Korolchuk Viktor I⁶,Tsunemi Taiji³,Hattori Nobutaka¹²³⁷^ORCID,Saiki Shinji²³^ORCID

Affiliation:

1. Research Institute for Diseases of Old Age Juntendo University Graduate School of Medicine Tokyo Japan

2. Division for Development of Autophagy Modulating Drugs Juntendo University Faculty of Medicine Tokyo Japan

3. Department of Neurology Juntendo University Faculty of Medicine Tokyo Japan

4. Biomedical Research Core Facilities Juntendo University Graduate School of Medicine Tokyo Japan

5. Department of Biology, Graduate School of Science and Engineering Chiba University Chiba Japan

6. Biosciences Institute, Faculty of Medical Sciences, Campus for Ageing and Vitality Newcastle University Newcastle upon Tyne UK

7. Neurodegenerative Disorders Collaborative Laboratory RIKEN Center for Brain Science Saitama Japan

Funder

Japan Society for the Promotion of Science

Naito Foundation

Publisher

EMBO

Subject

General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,Molecular Biology,General Neuroscience

Link

https://onlinelibrary.wiley.com/doi/pdf/10.15252/embj.2022111476

Reference60 articles.

1. Lysosomal metabolomics reveals V-ATPase- and mTOR-dependent regulation of amino acid efflux from lysosomes

2. Acrolein-mediated alpha-synuclein pathology involvement in the early post-injury pathogenesis of mild blast-induced Parkinsonian neurodegeneration

3. Acrolein-mediated neuronal cell death and alpha-synuclein aggregation: Implications for Parkinson's disease

4. Lysosomes as dynamic regulators of cell and organismal homeostasis

5. TRPA1 Mediates the Inflammatory Actions of Environmental Irritants and Proalgesic Agents

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