Prominin‐1 controls stem cell activation by orchestrating ciliary dynamics

Author:

Singer Donald1,Thamm Kristina2,Zhuang Heng13,Karbanová Jana2,Gao Yan14,Walker Jemma Victoria1,Jin Heng56,Wu Xiangnan7,Coveney Clarissa R8,Marangoni Pauline7,Lu Dongmei9,Grayson Portia Rebecca Clare1,Gulsen Tulay1,Liu Karen J10,Ardu Stefano11,Wann Angus KT8,Luo Shouqing12ORCID,Zambon Alexander C13,Jetten Anton M14ORCID,Tredwin Christopher1,Klein Ophir D715ORCID,Attanasio Massimo5,Carmeliet Peter1617ORCID,Huttner Wieland B18ORCID,Corbeil Denis2ORCID,Hu Bing1ORCID

Affiliation:

1. Peninsula Dental School University of Plymouth Plymouth UK

2. Tissue Engineering Laboratories, Biotechnology Center and Center for Molecular and Cellular Bioengineering Technische Universität Dresden Dresden Germany

3. Department of Cariology, Endodontology and Operative Dentistry Peking University School and Hospital of Stomatology Beijing China

4. Department of Orthodontics School of Stomatology Capital Medical University Beijing China

5. Department of Internal Medicine University of Iowa Iowa City IA USA

6. Department of Emergency Medicine Tianjin Medical University General Hospital Tianjin China

7. Program in Craniofacial Biology and Department of Orofacial Sciences University of California San Francisco CA USA

8. Arthritis Research UK Centre for Osteoarthritis Pathogenesis Kennedy Institute Nuffield Department for Orthopaedics, Rheumatology, and Musculoskeletal Sciences University of Oxford Oxford UK

9. Department of Internal Medicine University of Texas Southwestern Medical Center Dallas TX USA

10. Centre for Craniofacial and Regenerative Biology King's College London London UK

11. Division of Cariology & Endodontology Dental School University of Geneva Geneva Switzerland

12. Peninsula Medical School University of Plymouth Plymouth UK

13. Biopharmaceutical Sciences Keck Graduate Institute Claremont CA USA

14. Cell Biology Section Division of Intramural Research National Institute of Environmental Health Sciences National Institutes of Health Research Triangle Park NC USA

15. Department of Pediatrics and Institute for Human Genetics University of California San Francisco CA USA

16. Department of Oncology Laboratory of Angiogenesis and Vascular Metabolism KU Leuven Leuven Belgium

17. VIB‐KU Leuven Center for Cancer Biology Leuven Belgium

18. Max Planck Institute of Molecular Cell Biology and Genetics Dresden Germany

Funder

National Institutes of Health

National Natural Science Foundation of China

Deutsche Forschungsgemeinschaft

H2020 European Research Council

European Regional Development Fund

Biotechnology and Biological Sciences Research Council

Publisher

EMBO

Subject

General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,Molecular Biology,General Neuroscience

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