ArfGAP1 inhibits mTORC1 lysosomal localization and activation-Reference-Cited by-同舟云学术

ArfGAP1 inhibits mTORC1 lysosomal localization and activation

Published:2021-05-14 Issue:12 Volume:40 Page:
ISSN:0261-4189
Container-title:The EMBO Journal
language:en
Short-container-title:EMBO J

Author:

Meng Delong¹²³^ORCID,Yang Qianmei¹²³,Melick Chase H¹²³^ORCID,Park Brenden C¹²³,Hsieh Ting‐Sung¹²³^ORCID,Curukovic Adna¹²³,Jeong Mi‐Hyeon¹²³,Zhang Junmei¹^ORCID,James Nicholas G⁴^ORCID,Jewell Jenna L¹²³^ORCID

Affiliation:

1. Department of Molecular Biology University of Texas Southwestern Medical Center Dallas TX USA

2. Harold C. Simmons Comprehensive Cancer Center University of Texas Southwestern Medical Center Dallas TX USA

3. Hamon Center for Regenerative Science and Medicine University of Texas Southwestern Medical Center Dallas TX USA

4. Department of Cell and Molecular Biology John A. Burns School of Medicine University of Hawaii Honolulu HI USA

Funder

Cancer Prevention and Research Institute of Texas

Welch Foundation

American Cancer Society

National Institutes of Health

Publisher

EMBO

Subject

General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,Molecular Biology,General Neuroscience

Link

https://onlinelibrary.wiley.com/doi/pdf/10.15252/embj.2020106412

Reference75 articles.

1. Lysosomal metabolomics reveals V-ATPase- and mTOR-dependent regulation of amino acid efflux from lysosomes

2. ARFGAP1 promotes AP-2-dependent endocytosis

3. A Tumor Suppressor Complex with GAP Activity for the Rag GTPases That Signal Amino Acid Sufficiency to mTORC1

4. Ragulator Is a GEF for the Rag GTPases that Signal Amino Acid Levels to mTORC1

5. Arginine-induced stimulation of protein synthesis and survival in IPEC-J2 cells is mediated by mTOR but not nitric oxide

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