Discrete cytosolic macromolecular BRAF complexes exhibit distinct activities and composition-Reference-Cited by-同舟云学术

Discrete cytosolic macromolecular BRAF complexes exhibit distinct activities and composition

Published:2017-01-16 Issue:5 Volume:36 Page:646-663
ISSN:0261-4189
Container-title:The EMBO Journal
language:en
Short-container-title:EMBO J

Author:

Diedrich Britta¹²,Rigbolt Kristoffer TG¹²,Röring Michael³,Herr Ricarda³,Kaeser‐Pebernard Stephanie⁴,Gretzmeier Christine¹²⁵,Murphy Robert F⁵⁶^ORCID,Brummer Tilman²³⁷⁸⁹^ORCID,Dengjel Jörn¹²⁴⁵⁷^ORCID

Affiliation:

1. Department of Dermatology Medical Center ‐ University of Freiburg Freiburg Germany

2. ZBSA Center for Biological Systems Analysis University of Freiburg Freiburg Germany

3. Faculty of Medicine Institute of Molecular Medicine and Cell Research (IMMZ) University of Freiburg Freiburg Germany

4. Department of Biology University of Fribourg Fribourg Switzerland

5. Freiburg Institute for Advanced Studies (FRIAS) University of Freiburg Freiburg Germany

6. Computational Biology Department and Department of Biomedical Engineering Carnegie Mellon University Pittsburgh PA USA

7. Centre for Biological Signalling Studies BIOSS University of Freiburg Freiburg Germany

8. Comprehensive Cancer Centre Freiburg Germany

9. German Cancer Consortium (DKTK) partner site Freiburg, and German Cancer Research Center (DKFZ) Heidelberg Germany

Funder

Deutsche Forschungsgemeinschaft

Bundesministerium für Bildung und Forschung

Alexander von Humboldt-Stiftung

Ministerium für Wissenschaft, Forschung und Kunst Baden-Württemberg

Publisher

EMBO

Subject

General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,Molecular Biology,General Neuroscience

Link

https://onlinelibrary.wiley.com/doi/pdf/10.15252/embj.201694732

Reference87 articles.

1. Overcoming Acquired BRAF Inhibitor Resistance in Melanoma via Targeted Inhibition of Hsp90 with Ganetespib

2. Clinical Acquired Resistance to RAF Inhibitor Combinations in BRAF-Mutant Colorectal Cancer through MAPK Pathway Alterations

3. It takes two to tango – signalling by dimeric Raf kinases

4. Sprouty2 Association with B-Raf Is Regulated by Phosphorylation and Kinase Conformation

5. Identification of novel ERK-mediated feedback phosphorylation sites at the C-terminus of B-Raf

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