Che‐1‐induced inhibition of mTOR pathway enables stress‐induced autophagy-Reference-Cited by-同舟云学术

Che‐1‐induced inhibition of mTOR pathway enables stress‐induced autophagy

Published:2015-03-14 Issue:9 Volume:34 Page:1214-1230
ISSN:0261-4189
Container-title:The EMBO Journal
language:en
Short-container-title:EMBO J

Author:

Desantis Agata¹,Bruno Tiziana¹,Catena Valeria¹²,De Nicola Francesca¹,Goeman Frauke³,Iezzi Simona¹,Sorino Cristina¹,Ponzoni Maurilio⁴,Bossi Gianluca⁵,Federico Vincenzo⁶,La Rosa Francesca¹,Ricciardi Maria Rosaria⁶,Lesma Elena⁷,De Meo Paolo D'Onorio⁸,Castrignanò Tiziana⁸,Petrucci Maria Teresa⁶,Pisani Francesco⁹,Chesi Marta¹⁰,Bergsagel P Leif¹⁰,Floridi Aristide¹,Tonon Giovanni¹¹,Passananti Claudio¹²,Blandino Giovanni³,Fanciulli Maurizio¹

Affiliation:

1. Epigenetics Laboratory Molecular Medicine Area Regina Elena National Cancer Institute Rome Italy

2. Department of Biotechnological and Applied Clinical Sciences University of L'Aquila L'Aquila Italy

3. Translational Oncogenomic Laboratory Molecular Medicine Area Regina Elena National Cancer Institute Rome Italy

4. Pathology and Myeloma Units Molecular Oncology Division San Raffaele Scientific Institute Milan Italy

5. Molecular Oncogenesis Laboratory Regina Elena National Cancer Institute Rome Italy

6. Division of Hematology Department of Cellular Biotechnologies and Hematology “Sapienza” University Rome Italy

7. Laboratory of Pharmacology Department of Health Sciences University of Milan Milan Italy

8. HPC CINECA Rome Italy

9. Hematology Laboratory Regina Elena National Cancer Institute Rome Italy

10. Comprehensive Cancer Center Mayo Clinic Arizona Scottsdale AZ USA

11. Functional Genomics of Cancer Unit Molecular Oncology Division San Raffaele Scientific Institute Milan Italy

12. Institute of Molecular Biology and Pathology CNR Department of Molecular Medicine “Sapienza” University Rome Italy

Publisher

EMBO

Subject

General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,Molecular Biology,General Neuroscience

Link

https://onlinelibrary.wiley.com/doi/pdf/10.15252/embj.201489920

Reference62 articles.

1. A SNP microarray and FISH-based procedure to detect allelic imbalances in multiple myeloma: An integrated genomics approach reveals a wide gene dosage effect

2. Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex

3. Che-1 affects cell growth by interfering with the recruitment of HDAC1 by Rb

4. Che-1 phosphorylation by ATM/ATR and Chk2 kinases activates p53 transcription and the G2/M checkpoint

5. Che-1 Promotes Tumor Cell Survival by Sustaining Mutant p53 Transcription and Inhibiting DNA Damage Response Activation

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