Ribonuclease H2 mutations induce a cGAS / STING ‐dependent innate immune response-Reference-Cited by-同舟云学术

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Ribonuclease H2 mutations induce a cGAS / STING ‐dependent innate immune response

Published:2016-02-22 Issue:8 Volume:35 Page:831-844
ISSN:0261-4189
Container-title:The EMBO Journal
language:en
Short-container-title:EMBO J

Author:

Mackenzie Karen J¹,Carroll Paula¹,Lettice Laura¹,Tarnauskaitė Žygimantė¹,Reddy Kaalak¹,Dix Flora¹,Revuelta Ailsa¹,Abbondati Erika²,Rigby Rachel E¹,Rabe Björn¹,Kilanowski Fiona¹,Grimes Graeme¹,Fluteau Adeline¹,Devenney Paul S¹,Hill Robert E¹,Reijns Martin AM¹,Jackson Andrew P¹

Affiliation:

1. MRC Human Genetics Unit MRC Institute of Genetics and Molecular Medicine The University of Edinburgh Edinburgh UK

2. Roslin Institute The University of Edinburgh Edinburgh UK

Funder

Medical Research Council

Newlife Foundation for Disabled Children

Publisher

EMBO

Subject

General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,Molecular Biology,General Neuroscience

Link

https://onlinelibrary.wiley.com/doi/pdf/10.15252/embj.201593339

Reference61 articles.

1. TREX1 Deficiency Triggers Cell-Autonomous Immunity in a cGAS-Dependent Manner

2. Intrinsic Self-DNA Triggers Inflammatory Disease Dependent on STING

3. Inflammation-driven carcinogenesis is mediated through STING

4. Site-specific recombination of a transgene in fertilized eggs by transient expression of Cre recombinase.

5. Mouse SAMHD1 Has Antiretroviral Activity and Suppresses a Spontaneous Cell-Intrinsic Antiviral Response

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