High‐resolution analysis of the conformational transition of pro‐apoptotic Bak at the lipid membrane-Reference-Cited by-同舟云学术

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High‐resolution analysis of the conformational transition of pro‐apoptotic Bak at the lipid membrane

Published:2021-09-15 Issue:20 Volume:40 Page:
ISSN:0261-4189
Container-title:The EMBO Journal
language:en
Short-container-title:The EMBO Journal

Author:

Sperl Laura E¹²,Rührnößl Florian³,Schiller Anita¹²,Haslbeck Martin³,Hagn Franz¹²^ORCID

Affiliation:

1. Bavarian NMR Center at the Department of Chemistry Technical University of Munich Garching Germany

2. Institute of Structural Biology Helmholtz Zentrum München Neuherberg Germany

3. Center for Functional Protein Assemblies and Department of Chemistry Technical University of Munich Garching Germany

Funder

Helmholtz Association

Deutsche Forschungsgemeinschaft

Publisher

EMBO

Subject

General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,Molecular Biology,General Neuroscience

Link

https://onlinelibrary.wiley.com/doi/pdf/10.15252/embj.2020107159

Reference94 articles.

1. Bcl-2-regulated apoptosis: mechanism and therapeutic potential

2. Dissociation of Bak α1 helix from the core and latch domains is required for apoptosis

3. Organization of the Mitochondrial Apoptotic BAK Pore

4. Bax, but not Bcl-xL, decreases the lifetime of planar phospholipid bilayer membranes at subnanomolar concentrations

5. Structure of detergent-activated BAK dimers derived from the inert monomer

Cited by 19 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Preferred inhibition of pro-apoptotic Bak by BclxL via a two-step mechanism;Cell Reports;2024-08

2. The C-terminal sequences of Bcl-2 family proteins mediate interactions that regulate cell death;Biochemical Journal;2024-07-10

3. Parkin-mediated ubiquitination inhibits BAK apoptotic activity by blocking its canonical hydrophobic groove;Communications Biology;2023-12-12

4. Mechanisms of BCL-2 family proteins in mitochondrial apoptosis;Nature Reviews Molecular Cell Biology;2023-07-12

5. Inhibition of BAK apoptotic activity by Parkin-mediated ubiquitination;2023-07-10

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