Single‐cell transcriptomics of LepR‐positive skeletal cells reveals heterogeneous stress‐dependent stem and progenitor pools

Author:

Mo Chunyang1,Guo Jingxin23,Qin Jiachen1,Zhang Xiaoying1,Sun Yuxi4,Wei Hanjing1,Cao Dandan1,Zhang Yiying1,Zhao Chengchen1ORCID,Xiong Yanhong1ORCID,Zhang Yong1,Sun Yao5,Shen Li236ORCID,Yue Rui17ORCID

Affiliation:

1. Institute for Regenerative Medicine Shanghai East Hospital Frontier Science Center for Stem Cell Research Shanghai Key Laboratory of Signaling and Disease Research School of Life Sciences and Technology Tongji University Shanghai China

2. MOE Key Laboratory of Biosystems Homeostasis & Protection and Zhejiang Provincial Key Laboratory for Cancer Molecular Cell Biology, Life Sciences Institute Zhejiang University Hangzhou China

3. Department of Orthopedics Surgery 2nd Affiliated Hospital School of Medicine Zhejiang University Hangzhou China

4. Department of Cardiology Shanghai Tenth People's Hospital Tongji University School of Medicine Shanghai China

5. Department of Implantology School & Hospital of Stomatology Shanghai Engineering Research Center of Tooth Restoration and Regeneration Tongji University Shanghai China

6. Hangzhou Innovation Center Zhejiang University Hangzhou China

7. Shanghai Institute of Stem Cell Research and Clinical Translation Shanghai China

Funder

Ministry of Science and Technology of the People's Republic of China

National Natural Science Foundation of China

Fundamental Research Funds for the Central Universities

Publisher

EMBO

Subject

General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,Molecular Biology,General Neuroscience

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