PGE 2 ‐EP3 axis promotes brown adipose tissue formation through stabilization of WTAP RNA methyltransferase

Author:

Tao Xixi1ORCID,Du Ronglu1ORCID,Guo Shumin1,Feng Xiangling1ORCID,Yu Tingting1,OuYang Qian2,Chen Qiaoli2ORCID,Fan Xutong1ORCID,Wang Xueqi1,Guo Chen3,Li Xiaozhou3,Xue Fengxia3,Chen Shuai2,Tong Minghan4,Lazarus Michael5ORCID,Zuo Shengkai1,Yu Ying1ORCID,Shen Yujun1ORCID

Affiliation:

1. Department of Pharmacology, Tianjin Key Laboratory of Inflammatory Biology, Center for Cardiovascular Diseases, Key Laboratory of Immune Microenvironment and Disease (Ministry of Education), The Province and Ministry Co‐sponsored Collaborative Innovation Center for Medical Epigenetics, School of Basic Medical Sciences Tianjin Medical University Tianjin China

2. State Key Laboratory of Pharmaceutical Biotechnology, MOE Key Laboratory of Model Animal for Disease Study, Model Animal Research Center, Nanjing Biomedical Research Institute Nanjing University Nanjing China

3. Department of Gynecology and Obstetrics, Tianjin Key Laboratory of Female Reproductive Health and Eugenics Tianjin Medical University General Hospital Tianjin China

4. State Key Laboratory of Molecular Biology, Shanghai Key Laboratory of Molecular Andrology, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences University of Chinese Academy of Sciences Shanghai China

5. International Institute for Integrative Sleep Medicine (WPI‐IIIS) University of Tsukuba Tsukuba City Japan

Funder

National Key Research and Development Program of China

National Natural Science Foundation of China

Publisher

EMBO

Subject

General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,Molecular Biology,General Neuroscience

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