PKM2‐TMEM33 axis regulates lipid homeostasis in cancer cells by controlling SCAP stability-Reference-Cited by-同舟云学术

PKM2‐TMEM33 axis regulates lipid homeostasis in cancer cells by controlling SCAP stability

Published:2021-09-06 Issue:22 Volume:40 Page:
ISSN:0261-4189
Container-title:The EMBO Journal
language:en
Short-container-title:EMBO J

Author:

Liu Fabao¹^ORCID,Ma Min²,Gao Ang¹,Ma Fengfei²,Ma Gui¹,Liu Peng³⁴,Jia Chenxi²^ORCID,Wang Yidan¹^ORCID,Donahue Kristine¹,Zhang Shengjie¹,Ong Irene M³⁴,Keles Sunduz⁵,Li Lingjun²⁶^ORCID,Xu Wei¹^ORCID

Affiliation:

1. McArdle Laboratory for Cancer Research University of Wisconsin‐Madison Madison WI USA

2. School of Pharmacy University of Wisconsin‐Madison Madison WI USA

3. Department of Biostatistics and Medical Informatics University of Wisconsin‐Madison Madison WI USA

4. UW Carbone Cancer Center School of Medicine and Public Health University of Wisconsin‐Madison Madison WI USA

5. Department of Statistics University of Wisconsin‐Madison Madison WI USA

6. Department of Chemistry University of Wisconsin‐Madison Madison WI USA

Funder

National Institutes of Health

National Cancer Institute

Publisher

EMBO

Subject

General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,Molecular Biology,General Neuroscience

Link

https://onlinelibrary.wiley.com/doi/pdf/10.15252/embj.2021108065

Reference54 articles.

1. Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis

2. Pharmacological Activation of Pyruvate Kinase M2 Inhibits CD4+ T Cell Pathogenicity and Suppresses Autoimmunity

3. A Homeostatic Shift Facilitates Endoplasmic Reticulum Proteostasis through Transcriptional Integration of Proteostatic Stress Response Pathways

4. Lipid metabolic reprogramming in cancer cells

5. Role of Nrf1 in antioxidant response element-mediated gene expression and beyond

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