TPL‐2 kinase induces phagosome acidification to promote macrophage killing of bacteria-Reference-Cited by-同舟云学术

TPL‐2 kinase induces phagosome acidification to promote macrophage killing of bacteria

Published:2021-04-21 Issue:10 Volume:40 Page:
ISSN:0261-4189
Container-title:The EMBO Journal
language:en
Short-container-title:EMBO J

Author:

Breyer Felix¹^ORCID,Härtlova Anetta²³^ORCID,Thurston Teresa⁴^ORCID,Flynn Helen R¹^ORCID,Chakravarty Probir¹^ORCID,Janzen Julia¹,Peltier Julien²,Heunis Tiaan²,Snijders Ambrosius P¹,Trost Matthias²^ORCID,Ley Steven C¹⁵^ORCID

Affiliation:

1. The Francis Crick Institute London UK

2. Biosciences Institute Newcastle University Newcastle‐upon‐Tyne UK

3. Wallenberg Centre for Molecular and Translational Medicine University of Gothenburg Gothenburg Sweden

4. Department of Infectious Diseases MRC Centre for Molecular Bacteriology & Infection Imperial College London London UK

5. Department of Immunology & Inflammation Centre for Molecular Immunology & Inflammation Imperial College London London UK

Funder

Medical Research Council

Cancer Research UK

Boehringer Ingelheim Fonds

Wellcome

Publisher

EMBO

Subject

General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,Molecular Biology,General Neuroscience

Link

https://onlinelibrary.wiley.com/doi/pdf/10.15252/embj.2020106188

Reference62 articles.

1. Tpl2 promotes neutrophil trafficking, oxidative burst, and bacterial killing

2. GsdmD p30 elicited by caspase-11 during pyroptosis forms pores in membranes

3. Mitogen-activated protein kinases in innate immunity

4. Diverse Toll-like receptors utilize Tpl2 to activate extracellular signal-regulated kinase (ERK) in hemopoietic cells

5. NF-κB1 p105 Negatively Regulates TPL-2 MEK Kinase Activity

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