PLK 4 deubiquitination by Spata2‐CYLD suppresses NEK7‐mediated NLRP3 inflammasome activation at the centrosome-Reference-Cited by-同舟云学术

PLK 4 deubiquitination by Spata2‐CYLD suppresses NEK7‐mediated NLRP3 inflammasome activation at the centrosome

Published:2019-11-25 Issue:2 Volume:39 Page:
ISSN:0261-4189
Container-title:The EMBO Journal
language:en
Short-container-title:EMBO J

Author:

Yang Xiao‐Dong¹^ORCID,Li Wenguo¹^ORCID,Zhang Shuangyan¹,Wu Dandan¹,Jiang Xiaoli¹,Tan Rong²,Niu Xiaoyin¹,Wang Qijun¹,Wu Xuefeng¹,Liu Zhiduo¹,Chen Lin‐Feng³,Qin Jun⁴,Su Bing¹⁵^ORCID

Affiliation:

1. Shanghai Institute of Immunology Department of Immunology and Microbiology, and the Minister of Education Key Laboratory of Cell Death and Differentiation Shanghai Jiao Tong University School of Medicine Shanghai China

2. Xiangya Hospital Central South University Changsha China

3. Department of Biochemistry University of Illinois at Urbana‐Champaign Urbana IL USA

4. Department of Biochemistry and Molecular Biology Baylor College of Medicine Houston TX USA

5. Yale University Institute for Immune Metabolism Shanghai Jiao Tong University School of Medicine Shanghai China

Funder

National Natural Science Foundation of China

Publisher

EMBO

Subject

General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,Molecular Biology,General Neuroscience

Link

https://onlinelibrary.wiley.com/doi/pdf/10.15252/embj.2019102201

Reference47 articles.

1. Differential Requirement for Caspase-1 Autoproteolysis in Pathogen-Induced Cell Death and Cytokine Processing

2. Inflammasomes: mechanism of assembly, regulation and signalling

3. PtdIns4P on dispersed trans-Golgi network mediates NLRP3 inflammasome activation

4. Systematic Discovery of TLR Signaling Components Delineates Viral-Sensing Circuits

5. The Inflammasome NLRs in Immunity, Inflammation, and Associated Diseases

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