LRRK2 is a negative regulator of Mycobacterium tuberculosis phagosome maturation in macrophages-Reference-Cited by-同舟云学术

LRRK2 is a negative regulator of Mycobacterium tuberculosis phagosome maturation in macrophages

Published:2018-05-22 Issue:12 Volume:37 Page:
ISSN:0261-4189
Container-title:The EMBO Journal
language:en
Short-container-title:EMBO J

Author:

Härtlova Anetta¹²,Herbst Susanne³⁴,Peltier Julien¹²,Rodgers Angela³,Bilkei‐Gorzo Orsolya¹,Fearns Antony³,Dill Brian D¹,Lee Heyne⁵,Flynn Rowan⁵,Cowley Sally A⁵^ORCID,Davies Paul¹,Lewis Patrick A⁶⁷,Ganley Ian G¹^ORCID,Martinez Jennifer⁸,Alessi Dario R¹^ORCID,Reith Alastair D⁹,Trost Matthias¹²^ORCID,Gutierrez Maximiliano G³^ORCID

Affiliation:

1. MRC Protein Phosphorylation and Ubiquitylation Unit University of Dundee Dundee UK

2. Newcastle University Newcastle‐upon‐Tyne UK

3. Host‐Pathogen Interactions in Tuberculosis Laboratory The Francis Crick Institute London UK

4. Crick‐GSK Biomedical LinkLabs GlaxoSmithKline Pharmaceuticals R&D Stevenage UK

5. Sir William Dunn School of Pathology University of Oxford Oxford UK

6. University of Reading Reading UK

7. UCL Institute of Neurology Queen Square London UK

8. NIEHS Research Triangle Park NC USA

9. Neurodegeneration Discovery Performance Unit RD Neurosciences GlaxoSmithKline Pharmaceuticals R&D Stevenage UK

Funder

Wellcome Trust

Oxford Martin School, University of Oxford

Francis Crick Institute

Medical Research Council

Publisher

EMBO

Subject

General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,Molecular Biology,General Neuroscience

Link

https://onlinelibrary.wiley.com/doi/pdf/10.15252/embj.201798694

Reference71 articles.

1. LRRK2 regulates autophagic activity and localizes to specific membrane microdomains in a novel human genomic reporter cellular model

2. Characterization of VPS34-IN1, a selective inhibitor of Vps34, reveals that the phosphatidylinositol 3-phosphate-binding SGK3 protein kinase is a downstream target of class III phosphoinositide 3-kinase

3. Triplex protein quantification based on stable isotope labeling by peptide dimethylation applied to cell and tissue lysates

4. Brain Penetrant LRRK2 Inhibitor

5. The role of leucine-rich repeat kinase 2 (LRRK2) in Parkinson's disease

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