Toxic gain of function from mutant FUS protein is crucial to trigger cell autonomous motor neuron loss-Reference-Cited by-同舟云学术

Toxic gain of function from mutant FUS protein is crucial to trigger cell autonomous motor neuron loss

Published:2016-03-08 Issue:10 Volume:35 Page:1077-1097
ISSN:0261-4189
Container-title:The EMBO Journal
language:en
Short-container-title:EMBO J

Author:

Scekic‐Zahirovic Jelena¹²,Sendscheid Oliver³⁴,El Oussini Hajer¹²,Jambeau Mélanie⁵⁶,Sun Ying⁵⁶,Mersmann Sina³⁴,Wagner Marina³⁴,Dieterlé Stéphane¹²,Sinniger Jérome¹²,Dirrig‐Grosch Sylvie¹²,Drenner Kevin⁵⁶,Birling Marie‐Christine⁷,Qiu Jinsong⁸,Zhou Yu⁸,Li Hairi⁸,Fu Xiang‐Dong⁸,Rouaux Caroline¹²,Shelkovnikova Tatyana⁹,Witting Anke¹⁰,Ludolph Albert C¹⁰,Kiefer Friedemann¹¹,Storkebaum Erik³⁴,Lagier‐Tourenne Clotilde⁵⁶,Dupuis Luc¹²

Affiliation:

1. Faculté de Médecine INSERM U1118 Strasbourg France

2. Université de Strasbourg UMR_S1118 Strasbourg France

3. Molecular Neurogenetics Laboratory Max Planck Institute for Molecular Biomedicine Muenster Germany

4. Faculty of Medicine University of Muenster Muenster Germany

5. Department of Neurosciences University of California San Diego La Jolla CA USA

6. Ludwig Institute for Cancer Research University of California San Diego, La Jolla CA USA

7. Institut Clinique de la souris Illkirch‐Graffenstaden France

8. Department of Cellular and Molecular Medicine University of California San Diego, La Jolla CA USA

9. University of Cardiff Cardiff UK

10. Department of Neurology University of Ulm Ulm Germany

11. Mammalian Cell Signaling Laboratory Department of Vascular Cell Biology Max Planck Institute for Molecular Biomedicine Muenster Germany

Funder

Association Française contre les Myopathies

Max-Planck-Gesellschaft

Studienstiftung des Deutschen Volkes

Publisher

EMBO

Subject

General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,Molecular Biology,General Neuroscience

Link

https://onlinelibrary.wiley.com/doi/pdf/10.15252/embj.201592559

Reference100 articles.

1. Axonal Transport of TDP-43 mRNA Granules Is Impaired by ALS-Causing Mutations

2. SnapShot: Spinal Cord Development

3. ALS-linked TDP-43 mutations produce aberrant RNA splicing and adult-onset motor neuron disease without aggregation or loss of nuclear TDP-43

4. TDP-43 regulates its mRNA levels through a negative feedback loop

5. Juvenile ALS with basophilic inclusions is a FUS proteinopathy with FUS mutations

Cited by 177 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Cryo-EM structures of functional and pathological amyloid ribonucleoprotein assemblies;Trends in Biochemical Sciences;2024-02

2. The sense of antisense therapies in ALS;Trends in Molecular Medicine;2024-01

3. Mimicking hypomethylation of FUS requires liquid–liquid phase separation to induce synaptic dysfunctions;Acta Neuropathologica Communications;2023-12-18

4. Exploring the brain epitranscriptome: perspectives from the NSAS summit;Frontiers in Neuroscience;2023-10-20

5. lncRNA Sequencing Reveals Neurodegeneration-Associated FUS Mutations Alter Transcriptional Landscape of iPS Cells That Persists in Motor Neurons;Cells;2023-10-16