Structural basis for processivity and antiviral drug toxicity in human mitochondrial DNA replicase-Reference-Cited by-同舟云学术

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Structural basis for processivity and antiviral drug toxicity in human mitochondrial DNA replicase

Published:2015-06-08 Issue:14 Volume:34 Page:1959-1970
ISSN:0261-4189
Container-title:The EMBO Journal
language:en
Short-container-title:EMBO J

Author:

Szymanski Michal R¹²,Kuznetsov Vladmir B¹²,Shumate Christie¹²,Meng Qingchao¹,Lee Young‐Sam¹,Patel Gayatri³,Patel Smita³,Yin Y Whitney¹²

Affiliation:

1. Department of Pharmacology and Toxicology University of Texas Medical Branch Galveston TX USA

2. Sealy Center for Structural Biology University of Texas Medical Branch Galveston TX USA

3. Biochemistry and Molecular Biology Rutgers‐Robert Wood Johnson Medical School Piscataway NJ USA

Publisher

EMBO

Subject

General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,Molecular Biology,General Neuroscience

Link

https://onlinelibrary.wiley.com/doi/pdf/10.15252/embj.201591520

Reference47 articles.

1. PHENIX: a comprehensive Python-based system for macromolecular structure solution

2. How E. coli DNA polymerase I (klenow fragment) distinguishes between deoxy- and dideoxynucleotides

3. Early-onset familial parkinsonism due toPOLGmutations

4. The mechanism of action of T7 DNA polymerase

5. Crystal structure of a bacteriophage T7 DNA replication complex at 2.2 Å resolution

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1. Structural basis for substrate binding and selection by human mitochondrial RNA polymerase;Nature Communications;2024-08-20

2. Deregulation of mitochondrial gene expression in cancer: mechanisms and therapeutic opportunities;British Journal of Cancer;2024-08-14

3. Structures of the mitochondrial single-stranded DNA binding protein with DNA and DNA polymerase γ;Nucleic Acids Research;2024-08-06

4. Coordinated DNA polymerization by Polγ and the region of LonP1 regulated proteolysis;Nucleic Acids Research;2024-06-27

5. A conserved polar residue plays a critical role in mismatch detection in A-family DNA polymerases;International Journal of Biological Macromolecules;2024-06

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